TE9A_HASHE
ID TE9A_HASHE Reviewed; 88 AA.
AC P0CI14;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 30-NOV-2010, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Augerpeptide Hhe9a;
DE AltName: Full=Hhe9.1;
DE Flags: Precursor;
OS Hastula hectica (Sea snail) (Impages hectica).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Neogastropoda; Conoidea; Terebridae; Hastula.
OX NCBI_TaxID=745793;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 52-88.
RC TISSUE=Venom, and Venom duct;
RX PubMed=17886885; DOI=10.1002/jez.b.21195;
RA Imperial J.S., Kantor Y., Watkins M., Heralde F.M. III, Stevenson B.,
RA Chen P., Hansson K., Stenflo J., Ownby J.P., Bouchet P., Olivera B.M.;
RT "Venomous auger snail Hastula (Impages) hectica (Linnaeus, 1758): molecular
RT phylogeny, foregut anatomy and comparative toxinology.";
RL J. Exp. Zool. B Mol. Dev. Evol. 308:744-756(2007).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC -!- DOMAIN: The cysteine framework is IX (C-C-C-C-C-C).
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DR AlphaFoldDB; P0CI14; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Cleavage on pair of basic residues; Direct protein sequencing;
KW Disulfide bond; Secreted; Signal; Toxin.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT PROPEP 22..49
FT /id="PRO_0000402146"
FT CHAIN 52..88
FT /note="Augerpeptide Hhe9a"
FT /id="PRO_0000402147"
FT DISULFID 56..71
FT /evidence="ECO:0000250"
FT DISULFID 61..73
FT /evidence="ECO:0000250"
FT DISULFID 67..86
FT /evidence="ECO:0000250"
SQ SEQUENCE 88 AA; 10002 MW; D0B766CC6F2F5B2F CRC64;
MMTKTGLVLL FAFLLVFPVS SLPMDAEAGH ARLEMDKRDA GNEAWTRLLK RYEENCGTEY
CTSKIGCPGR CVCKEYNYNG EITRRCRA