ID   TEAB_HALED              Reviewed;         193 AA.
AC   E1VBK2; Q8VPB2;
DT   16-APR-2014, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 1.
DT   25-MAY-2022, entry version 43.
DE   RecName: Full=Ectoine TRAP transporter small permease protein TeaB;
GN   Name=teaB; OrderedLocusNames=HELO_4275;
OS   Halomonas elongata (strain ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198
OS   / 1H9).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Oceanospirillales;
OC   Halomonadaceae; Halomonas.
OX   NCBI_TaxID=768066;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION, SUBUNIT, DISRUPTION PHENOTYPE,
RP   AND GENE NAME.
RC   STRAIN=ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9;
RX   PubMed=12003950; DOI=10.1128/jb.184.11.3078-3085.2002;
RA   Grammann K., Volke A., Kunte H.J.;
RT   "New type of osmoregulated solute transporter identified in halophilic
RT   members of the bacteria domain: TRAP transporter TeaABC mediates uptake of
RT   ectoine and hydroxyectoine in Halomonas elongata DSM 2581(T).";
RL   J. Bacteriol. 184:3078-3085(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33173 / DSM 2581 / NBRC 15536 / NCIMB 2198 / 1H9;
RX   PubMed=20849449; DOI=10.1111/j.1462-2920.2010.02336.x;
RA   Schwibbert K., Marin-Sanguino A., Bagyan I., Heidrich G., Lentzen G.,
RA   Seitz H., Rampp M., Schuster S.C., Klenk H.P., Pfeiffer F., Oesterhelt D.,
RA   Kunte H.J.;
RT   "A blueprint of ectoine metabolism from the genome of the industrial
RT   producer Halomonas elongata DSM 2581(T).";
RL   Environ. Microbiol. 13:1973-1994(2011).
CC   -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC       transport system TeaABC involved in the uptake of ectoine and
CC       hydroxyectoine in response to osmotic upshock. Probably functions as a
CC       recovery system for synthesized ectoine that leaks out of the cell.
CC       {ECO:0000269|PubMed:12003950}.
CC   -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC       protein TeaA, and the two transmembrane proteins TeaB and TeaC.
CC       {ECO:0000269|PubMed:12003950}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Deletion abolishes accumulation of ectoine from
CC       the medium. {ECO:0000269|PubMed:12003950}.
CC   -!- SIMILARITY: Belongs to the TRAP transporter small permease family.
CC       {ECO:0000305}.
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DR   EMBL; AY061646; AAL29685.2; -; Genomic_DNA.
DR   EMBL; FN869568; CBV44159.1; -; Genomic_DNA.
DR   RefSeq; WP_013334029.1; NC_014532.2.
DR   AlphaFoldDB; E1VBK2; -.
DR   STRING; 768066.HELO_4275; -.
DR   TCDB; 2.A.56.1.11; the tripartite atp-independent periplasmic transporter (trap-t) family.
DR   EnsemblBacteria; CBV44159; CBV44159; HELO_4275.
DR   KEGG; hel:HELO_4275; -.
DR   eggNOG; COG3090; Bacteria.
DR   HOGENOM; CLU_086356_3_7_6; -.
DR   OMA; RHIRMSA; -.
DR   Proteomes; UP000008707; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007387; TRAP_DctQ.
DR   PANTHER; PTHR35011; PTHR35011; 1.
DR   Pfam; PF04290; DctQ; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..193
FT                   /note="Ectoine TRAP transporter small permease protein
FT                   TeaB"
FT                   /id="PRO_0000428830"
FT   TRANSMEM        33..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        103..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   193 AA;  21478 MW;  2E2F0552ED947A9A CRC64;
     MTDEEEAEKH YHSGLPGILG TIDTLISKLE AIILALGVLL MATNTVANVI GRFALGESLF
     FTGEVNRILI IMITFAGIGY AARHGRHIRM SAIYDALPVG GRRALMIVIS LFTSLVMFFL
     MYYSVHYVLD LYDKGRILPA LGFPIFIIYV WVPLGFLITG IQYLFTAIKN LTSRDVYLST
     SVVDGYKDTE TEV