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TEAN2_DANRE
ID   TEAN2_DANRE             Reviewed;         210 AA.
AC   B0UYI1;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Transcription elongation factor A N-terminal and central domain-containing protein 2;
GN   Name=tceanc2; ORFNames=si:dkey-63k7.9;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen;
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00649,
CC       ECO:0000255|PROSITE-ProRule:PRU00651}.
CC   -!- SIMILARITY: Belongs to the TCEANC2 family. {ECO:0000305}.
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DR   EMBL; CR450845; CAQ13685.1; -; Genomic_DNA.
DR   RefSeq; NP_001333180.1; NM_001346251.1.
DR   AlphaFoldDB; B0UYI1; -.
DR   SMR; B0UYI1; -.
DR   STRING; 7955.ENSDARP00000085930; -.
DR   PaxDb; B0UYI1; -.
DR   Ensembl; ENSDART00000091497; ENSDARP00000085930; ENSDARG00000062919.
DR   GeneID; 567698; -.
DR   KEGG; dre:567698; -.
DR   CTD; 127428; -.
DR   ZFIN; ZDB-GENE-070705-486; tceanc2.
DR   eggNOG; KOG1105; Eukaryota.
DR   GeneTree; ENSGT00390000014384; -.
DR   HOGENOM; CLU_086873_0_0_1; -.
DR   InParanoid; B0UYI1; -.
DR   OMA; FALKHKP; -.
DR   OrthoDB; 1403676at2759; -.
DR   PhylomeDB; B0UYI1; -.
DR   TreeFam; TF331911; -.
DR   PRO; PR:B0UYI1; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 2.
DR   Bgee; ENSDARG00000062919; Expressed in early embryo and 22 other tissues.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006351; P:transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.472.30; -; 1.
DR   Gene3D; 1.20.930.10; -; 1.
DR   InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR003618; TFIIS_cen_dom.
DR   InterPro; IPR036575; TFIIS_cen_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   Pfam; PF08711; Med26; 1.
DR   Pfam; PF07500; TFIIS_M; 1.
DR   SMART; SM00509; TFS2N; 1.
DR   SUPFAM; SSF46942; SSF46942; 1.
DR   SUPFAM; SSF47676; SSF47676; 1.
DR   PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..210
FT                   /note="Transcription elongation factor A N-terminal and
FT                   central domain-containing protein 2"
FT                   /id="PRO_0000406044"
FT   DOMAIN          39..114
FT                   /note="TFIIS N-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00649"
FT   DOMAIN          131..210
FT                   /note="TFIIS central"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00651"
SQ   SEQUENCE   210 AA;  24667 MW;  C4A31E5E13C29F42 CRC64;
     MDKFVVRLPK DDMMKQESKH ERNYKQATLE SLRRVVVIED IERYKSILEL PGQPKENMIE
     ALKELDKKVP SREVLKSTRI GHTVNNLRKH SDDPEIKSLA KEVYKHWRTF IEEHANKPSI
     EVRCDKQTES LRSNAKKLLS EAIEMKVDHE LVENIEREVF HQSSRLVSGA YRRTVRALVF
     ALKHKPELRV QVKDGKLPVN VFVKSYKKKS
 
 
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