ID   TEAN2_RAT               Reviewed;         207 AA.
AC   Q5XIC7;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 98.
DE   RecName: Full=Transcription elongation factor A N-terminal and central domain-containing protein 2;
GN   Name=Tceanc2;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Heart;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00649,
CC       ECO:0000255|PROSITE-ProRule:PRU00651}.
CC   -!- SIMILARITY: Belongs to the TCEANC2 family. {ECO:0000305}.
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DR   EMBL; BC083757; AAH83757.1; -; mRNA.
DR   RefSeq; NP_001014282.1; NM_001014260.2.
DR   AlphaFoldDB; Q5XIC7; -.
DR   SMR; Q5XIC7; -.
DR   STRING; 10116.ENSRNOP00000049524; -.
DR   iPTMnet; Q5XIC7; -.
DR   PhosphoSitePlus; Q5XIC7; -.
DR   PaxDb; Q5XIC7; -.
DR   PRIDE; Q5XIC7; -.
DR   DNASU; 366431; -.
DR   Ensembl; ENSRNOT00000048784; ENSRNOP00000049524; ENSRNOG00000009398.
DR   GeneID; 366431; -.
DR   KEGG; rno:366431; -.
DR   UCSC; RGD:1359481; rat.
DR   CTD; 127428; -.
DR   RGD; 1359481; Tceanc2.
DR   eggNOG; KOG1105; Eukaryota.
DR   GeneTree; ENSGT00390000014384; -.
DR   HOGENOM; CLU_086873_0_0_1; -.
DR   InParanoid; Q5XIC7; -.
DR   OMA; FALKHKP; -.
DR   OrthoDB; 1403676at2759; -.
DR   PhylomeDB; Q5XIC7; -.
DR   PRO; PR:Q5XIC7; -.
DR   Proteomes; UP000002494; Chromosome 5.
DR   Bgee; ENSRNOG00000009398; Expressed in testis and 19 other tissues.
DR   Genevisible; Q5XIC7; RN.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0006351; P:transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.472.30; -; 1.
DR   Gene3D; 1.20.930.10; -; 1.
DR   InterPro; IPR003617; TFIIS/CRSP70_N_sub.
DR   InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR   InterPro; IPR003618; TFIIS_cen_dom.
DR   InterPro; IPR036575; TFIIS_cen_dom_sf.
DR   InterPro; IPR017923; TFIIS_N.
DR   Pfam; PF08711; Med26; 1.
DR   SMART; SM00509; TFS2N; 1.
DR   SUPFAM; SSF46942; SSF46942; 1.
DR   SUPFAM; SSF47676; SSF47676; 1.
DR   PROSITE; PS51321; TFIIS_CENTRAL; 1.
DR   PROSITE; PS51319; TFIIS_N; 1.
PE   2: Evidence at transcript level;
KW   Acetylation; Nucleus; Reference proteome.
FT   CHAIN           1..207
FT                   /note="Transcription elongation factor A N-terminal and
FT                   central domain-containing protein 2"
FT                   /id="PRO_0000286576"
FT   DOMAIN          39..113
FT                   /note="TFIIS N-terminal"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00649"
FT   DOMAIN          130..207
FT                   /note="TFIIS central"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00651"
FT   MOD_RES         1
FT                   /note="N-acetylmethionine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96MN5"
SQ   SEQUENCE   207 AA;  24299 MW;  1EF84F06CC58220A CRC64;
     MDKFVIRTPR IQNSPKKKLK EKVYKQATIE SLKRVVVIED IKRWKTVLEL PEQTKENLVA
     ALQELKKKIP SREVLRSTRI GHAVNKVRRH SDPEVAGLAK EVYTEWKTFI ENHLDRPSIE
     VHSDPKTESF RKNAQKLLSE ALELKMDHLL VENIERETFH LCSRLINRPY RRTVRALVFT
     LKHRAEIREQ VKSGTLPVGT FVQTHKK