ID   TEBH_EUPCR              Reviewed;         460 AA.
AC   Q06183;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Telomere-binding protein homolog;
OS   Euplotes crassus.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata; Spirotrichea;
OC   Hypotrichia; Euplotida; Euplotidae; Moneuplotes.
OX   NCBI_TaxID=5936;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1480483; DOI=10.1093/nar/20.24.6621;
RA   Wang W., Skopp R., Scofield M., Price C.;
RT   "Euplotes crassus has genes encoding telomere-binding proteins and
RT   telomere-binding protein homologs.";
RL   Nucleic Acids Res. 20:6621-6629(1992).
CC   -!- FUNCTION: May bind telomeric T4G4 sequences.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. Chromosome, telomere
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the telombin family. {ECO:0000305}.
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DR   EMBL; M96819; AAA29128.1; -; Genomic_DNA.
DR   PIR; S35525; S35525.
DR   AlphaFoldDB; Q06183; -.
DR   SMR; Q06183; -.
DR   GO; GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0043047; F:single-stranded telomeric DNA binding; IEA:InterPro.
DR   GO; GO:0016233; P:telomere capping; IEA:InterPro.
DR   Gene3D; 2.40.50.140; -; 3.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR028389; POT1.
DR   InterPro; IPR011564; Telomer_end-bd_POT1/Cdc13.
DR   InterPro; IPR003415; Telomere-bd_alpha.
DR   PANTHER; PTHR14513; PTHR14513; 1.
DR   Pfam; PF02765; POT1; 2.
DR   PIRSF; PIRSF015848; TEBP_alpha; 1.
DR   SMART; SM00976; Telo_bind; 1.
DR   SUPFAM; SSF50249; SSF50249; 3.
PE   3: Inferred from homology;
KW   Chromosome; DNA-binding; Nucleus; Telomere.
FT   CHAIN           1..460
FT                   /note="Telomere-binding protein homolog"
FT                   /id="PRO_0000121734"
SQ   SEQUENCE   460 AA;  53360 MW;  ED1C141385A0B5FE CRC64;
     MKRRTDLDTK SSRKVYKKYE YTEIGSIEEE NEASINFYAV VIDACFPYKV DEKKYMCYLK
     VIDTTHNVKE GDDNFAIVAL QSRKFEDLPI IQRCGDIIRV HRAEYNYKDD QHYFKLNMSY
     SSSWALFSAD EEVAPEVIKD EGDDFTYRSY AYSGKQYNFD TQDQKLLKNT RAWNKSYFAK
     NDVIIDEMYT PLSQARQEEG DFNVVGKVTQ IVHRDYYTSD LRVKDTSKAT WFLTVSRRKF
     PRLYEGVIIK IRSVNIDSET ERERCLELAP HSNIMTFVPF SRLAKSLDSQ ISLSPDKVDK
     ELIKKVILTE PVLATTTFGD YSELPLTELS EIFEDVTDKD AVFRARFSIL KITPDRVEDY
     VEEYTPKGAP RSKPVYKVQF LIKDPSTALN DNLYKIYLYS HGDLGKEFFP GVDPSSAQTP
     SGHSKLRKYA STLMKFNVHI DAVLEKVGGA FFIRDTEMKF