TED6_ARATH
ID TED6_ARATH Reviewed; 116 AA.
AC Q8LBX7;
DT 11-DEC-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein TRACHEARY ELEMENT DIFFERENTIATION-RELATED 6 {ECO:0000303|PubMed:19383897};
GN Name=TED6 {ECO:0000303|PubMed:19383897};
GN OrderedLocusNames=At1g43790 {ECO:0000312|Araport:AT1G43790};
GN ORFNames=F28H19.19 {ECO:0000312|EMBL:AC006423};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, DISRUPTION PHENOTYPE, TISSUE SPECIFICITY, INTERACTION WITH
RP CESA7/IRX3, AND DEVELOPMENTAL STAGE.
RX PubMed=19383897; DOI=10.1105/tpc.108.059154;
RA Endo S., Pesquet E., Yamaguchi M., Tashiro G., Sato M., Toyooka K.,
RA Nishikubo N., Udagawa-Motose M., Kubo M., Fukuda H., Demura T.;
RT "Identifying new components participating in the secondary cell wall
RT formation of vessel elements in zinnia and Arabidopsis.";
RL Plant Cell 21:1155-1165(2009).
CC -!- FUNCTION: Involved in the secondary cell wall (SCW) formation of vessel
CC elements (e.g. protoxylem and metaxylem), thus promoting tracheary
CC element (TE) differentiation. {ECO:0000269|PubMed:19383897}.
CC -!- SUBUNIT: Interacts with CESA7/IRX3, a subunit of the secondary cell
CC wall (SCW)-related cellulose synthase complex.
CC {ECO:0000269|PubMed:19383897}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:C1PGW0};
CC Single-pass membrane protein {ECO:0000255}. Secreted, cell wall
CC {ECO:0000250|UniProtKB:C1PGW0}.
CC -!- TISSUE SPECIFICITY: Expressed preferentially in differentiating vessel
CC elements in seedlings. {ECO:0000269|PubMed:19383897}.
CC -!- DEVELOPMENTAL STAGE: Restricted to differentiating vessel elements of
CC protoxylem and metaxylem. {ECO:0000269|PubMed:19383897}.
CC -!- DISRUPTION PHENOTYPE: Conditionnal double mutant plants lacking both
CC TED6 and TED7 have aberrant secondary cell wall (SCW) formation of root
CC vessel elements. {ECO:0000269|PubMed:19383897}.
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DR EMBL; AC006423; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE31997.1; -; Genomic_DNA.
DR EMBL; BT024569; ABD38908.1; -; mRNA.
DR EMBL; AY086934; AAM64498.1; -; mRNA.
DR RefSeq; NP_564487.1; NM_103507.2.
DR AlphaFoldDB; Q8LBX7; -.
DR IntAct; Q8LBX7; 2.
DR STRING; 3702.AT1G43790.1; -.
DR PaxDb; Q8LBX7; -.
DR PRIDE; Q8LBX7; -.
DR ProteomicsDB; 187091; -.
DR EnsemblPlants; AT1G43790.1; AT1G43790.1; AT1G43790.
DR GeneID; 840976; -.
DR Gramene; AT1G43790.1; AT1G43790.1; AT1G43790.
DR KEGG; ath:AT1G43790; -.
DR Araport; AT1G43790; -.
DR TAIR; locus:2029132; AT1G43790.
DR eggNOG; ENOG502STV4; Eukaryota.
DR HOGENOM; CLU_2100240_0_0_1; -.
DR InParanoid; Q8LBX7; -.
DR OMA; CRKNERI; -.
DR OrthoDB; 1587677at2759; -.
DR PhylomeDB; Q8LBX7; -.
DR PRO; PR:Q8LBX7; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8LBX7; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009505; C:plant-type cell wall; ISS:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR GO; GO:0044568; C:secondary cell wall cellulose synthase complex; IDA:UniProtKB.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0009834; P:plant-type secondary cell wall biogenesis; IGI:TAIR.
DR GO; GO:2000652; P:regulation of secondary cell wall biogenesis; IMP:UniProtKB.
DR GO; GO:1905177; P:tracheary element differentiation; IMP:UniProtKB.
DR InterPro; IPR044950; TED6/7.
DR PANTHER; PTHR35697; PTHR35697; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Cell wall; Cell wall biogenesis/degradation;
KW Developmental protein; Membrane; Reference proteome; Secreted;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..116
FT /note="Protein TRACHEARY ELEMENT DIFFERENTIATION-RELATED 6"
FT /id="PRO_0000448736"
FT TOPO_DOM 1..24
FT /note="Extracellular"
FT /evidence="ECO:0000305"
FT TRANSMEM 25..45
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 46..116
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
SQ SEQUENCE 116 AA; 13007 MW; 7C6A68895D33EC5E CRC64;
MASTDSVYRP TPTPDHDTTV VVVVFVSLGC VMFLAFLAFV IWFLIKKRSR KHRERSEAVR
VDEHFKMKEA IVEGPNGQKS VVLSVEDDVK IEDAIKREEK DLKKDGGVGS SVVSRS
