ID   TEG1_EHV1B              Reviewed;         747 AA.
AC   P28937; Q6DLJ7;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   02-JUN-2021, entry version 73.
DE   RecName: Full=Tegument protein UL46 homolog;
DE   AltName: Full=Tegument protein VP11/12 homolog;
GN   ORFNames=14;
OS   Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=31520;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA   Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus-1.";
RL   Virology 189:304-316(1992).
CC   -!- FUNCTION: Modulates alpha trans-inducing factor-dependent activation of
CC       alpha genes. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10230}.
CC       Host cell membrane {ECO:0000250|UniProtKB:P10230}; Peripheral membrane
CC       protein {ECO:0000250|UniProtKB:P10230}.
CC   -!- SIMILARITY: Belongs to the herpesviridae HHV-1 VP11/12 protein family.
CC       {ECO:0000305}.
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DR   EMBL; AY665713; AAT67271.1; -; Genomic_DNA.
DR   PIR; F36796; TNBEA2.
DR   RefSeq; YP_053059.1; NC_001491.2.
DR   GeneID; 1487517; -.
DR   KEGG; vg:1487517; -.
DR   Proteomes; UP000001189; Genome.
DR   GO; GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   InterPro; IPR005051; Herpes_UL46.
DR   Pfam; PF03387; Herpes_UL46; 1.
PE   3: Inferred from homology;
KW   Activator; Host cell membrane; Host membrane; Membrane; Phosphoprotein;
KW   Reference proteome; Transcription; Transcription regulation; Virion;
KW   Virion tegument.
FT   CHAIN           1..747
FT                   /note="Tegument protein UL46 homolog"
FT                   /id="PRO_0000115795"
FT   REGION          437..484
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          525..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          611..665
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          689..747
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        466..484
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        525..557
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        633..651
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        703..724
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   747 AA;  82310 MW;  AC660F345C7B5F26 CRC64;
     MDGGGSSSWT HVSKNLIERR AVKGCLLPTP SDVMDAAVMA LKDVTENIVG QQLFSVDRTN
     ALSVIHTNEV PESIIATAIA RDTSRDYLRE YEGAAKCNLA ATDLSHDEMW EVVIKRYWRY
     LRESSGAEVV DRGAVGQATQ SVLSVLLLQS TFGKKRLSKN PFKHKGPNVG YKSNLEDLRS
     AFTKIEKYMY YMRPNDPMTK SEDTELRLHE LLAYVTTCYR WLLWFMDLTD AKVLRNIDKG
     PVITHGPRES RPPDELVRRH LKSGPAISAG TGVALTLSTA TADALIVLLR MSVSWTSHSW
     KSNTHGVTGA IVAAVELVTL IHHHLQYIIN TVFAGYVCWL DGGVENSYLN SALRSQGRFD
     HFVGKLVPIM ATLSWANMEK GTVMWFKYAL AKSIVCHGSP TQHYLTVLES IASKRTGACP
     PQGSTFGRNP SGFPGQFCCP PQGPLPAPPN SKTRGTFRRC RPGSLRSSRQ LPTSPPSNIV
     SPRTNPAIEG STAAKNVQGA ETIQVRSSGE FNDCIWYING AYPHQRSDSS SSDNSTCSST
     ETQYITLPST PSPTGDVVYT NPLLGPDEEV DASPQPVDPM SDYSAPKNPD YMRPRSTLVE
     EVWQLRDSDY TPYMRPSRAG RSRVRVEDQT LEPSSPAGCN PPANSPENDS DDAAVDSPPI
     SPEVVYGTFR PRAKCVYDQY GLTALAALSA SRAKARRTRP GPTQPDVCRE RDEESAEPRH
     DGFIRRTMST TGPPRKHPDQ TERVSSL