TEG3_GAHVM
ID TEG3_GAHVM Reviewed; 243 AA.
AC Q9E6Q3;
DT 05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 23-FEB-2022, entry version 53.
DE RecName: Full=Tegument protein UL14 homolog;
GN Name=MDV026;
OS Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's
OS disease herpesvirus type 1).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus.
OX NCBI_TaxID=10389;
OH NCBI_TaxID=9031; Gallus gallus (Chicken).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=10933706; DOI=10.1128/jvi.74.17.7980-7988.2000;
RA Tulman E.R., Afonso C.L., Lu Z., Zsak L., Rock D.L., Kutish G.F.;
RT "The genome of a very virulent Marek's disease virus.";
RL J. Virol. 74:7980-7988(2000).
CC -!- FUNCTION: Contributes to the nuclear transport of the viral
CC transcriptional activator VP16 homolog during the early phase of
CC infection. Therefore, participates indirectly in the regulation of the
CC immediate-early gene expression. Additionally, seems to be important
CC for efficient nuclear targeting of capsids (By similarity).
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cytoplasm
CC {ECO:0000250}. Host nucleus {ECO:0000250}.
CC -!- PTM: Phosphorylated. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL14 protein
CC family. {ECO:0000305}.
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DR EMBL; AF243438; AAG14206.1; -; Genomic_DNA.
DR RefSeq; YP_001033942.1; NC_002229.3.
DR SMR; Q9E6Q3; -.
DR GeneID; 4811487; -.
DR KEGG; vg:4811487; -.
DR Proteomes; UP000008072; Genome.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR InterPro; IPR005207; Herpes_UL14.
DR Pfam; PF03580; Herpes_UL14; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host nucleus; Reference proteome; Virion; Virion tegument.
FT CHAIN 1..243
FT /note="Tegument protein UL14 homolog"
FT /id="PRO_0000406524"
SQ SEQUENCE 243 AA; 27861 MW; D4D342199C06484E CRC64;
MFAVSAMRRR RRRILAECRT REAVYKERTL ELLSQGVETD DPEFIEVFTS ARNAHSDYKA
QLRSNMRLEA TDRKTKIIQR HIDEQLDRRL ILDINRKLLN PKLQLQLDQT EEAILEKEDI
LAQTIDDITL NDSITNTDEL DEESEALLTK WILNQKTKKR PTVAKTAIAP TAHGLQTKVS
RNVFITGKDD LVQPTDLGQP STHEVITCTS RERIIHPDGI HTEIYTTEDV SPTILDDVSD
SCV