ID   TEG3_HHV2H              Reviewed;         219 AA.
AC   P89437;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   23-FEB-2022, entry version 56.
DE   RecName: Full=Tegument protein UL14;
GN   ORFNames=UL14;
OS   Human herpesvirus 2 (strain HG52) (HHV-2) (Human herpes simplex virus 2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus.
OX   NCBI_TaxID=10315;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=9499055; DOI=10.1128/jvi.72.3.2010-2021.1998;
RA   Dolan A., Jamieson F.E., Cunningham C., Barnett B.C., McGeoch D.J.;
RT   "The genome sequence of herpes simplex virus type 2.";
RL   J. Virol. 72:2010-2021(1998).
CC   -!- FUNCTION: Contributes to the nuclear transport of the viral
CC       transcriptional activator VP16 during the early phase of infection.
CC       Therefore, participates indirectly in the regulation of the immediate-
CC       early gene expression. Additionally, seems to be important for
CC       efficient nuclear targeting of capsids (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Host nucleus {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL14 protein
CC       family. {ECO:0000305}.
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DR   EMBL; Z86099; CAB06774.1; -; Genomic_DNA.
DR   RefSeq; YP_009137165.1; NC_001798.2.
DR   SMR; P89437; -.
DR   PRIDE; P89437; -.
DR   DNASU; 1487297; -.
DR   GeneID; 1487297; -.
DR   KEGG; vg:1487297; -.
DR   Proteomes; UP000001874; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005207; Herpes_UL14.
DR   Pfam; PF03580; Herpes_UL14; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host nucleus; Phosphoprotein; Reference proteome; Virion;
KW   Virion tegument.
FT   CHAIN           1..219
FT                   /note="Tegument protein UL14"
FT                   /id="PRO_0000385151"
FT   REGION          159..219
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        186..202
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   219 AA;  23871 MW;  FAC1C1B5C0AECC8A CRC64;
     MSRDASHAAL RRRLAETHLR AEVYRDQTLQ LHREGVSTQD PRFVGAFMAA KAAHLELEAR
     LKSRARLEMM RQRATCVKIR VEEQAARRDF LTAHRRYLDP ALSERLDAAD DRLADQEEQL
     EEAAANASLW GDGDLADGWM SPGDSDLLVM WQLTSAPKVH TDAPSRPGSR PTYTPSAAGR
     PDAQAAPPPE TAPSPEPAPG PAADPASGSG FARDCPDGE