TEG3_SUHVN
ID TEG3_SUHVN Reviewed; 159 AA.
AC P30661;
DT 01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-APR-1993, sequence version 1.
DT 23-FEB-2022, entry version 44.
DE RecName: Full=Tegument protein UL14;
GN Name=UL14;
OS Suid herpesvirus 1 (strain NIA-3) (SuHV-1) (Pseudorabies virus (strain
OS NIA-3)).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX NCBI_TaxID=10349;
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1323689; DOI=10.1128/jvi.66.9.5200-5209.1992;
RA de Wind N., Domen J., Berns A.A.;
RT "Herpesviruses encode an unusual protein-serine/threonine kinase which is
RT nonessential for growth in cultured cells.";
RL J. Virol. 66:5200-5209(1992).
CC -!- FUNCTION: Contributes to the nuclear transport of the viral
CC transcriptional activator VP16 during the early phase of infection.
CC Therefore, participates indirectly in the regulation of the immediate-
CC early gene expression. Additionally, seems to be important for
CC efficient nuclear targeting of capsids (By similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cytoplasm
CC {ECO:0000250}. Host nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL14 protein
CC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; M94870; AAA47480.1; -; Genomic_DNA.
DR PIR; A42744; WZBEE3.
DR RefSeq; YP_068361.1; NC_006151.1.
DR SMR; P30661; -.
DR GeneID; 2952529; -.
DR KEGG; vg:2952529; -.
DR GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR InterPro; IPR005207; Herpes_UL14.
DR Pfam; PF03580; Herpes_UL14; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host nucleus; Virion; Virion tegument.
FT CHAIN 1..159
FT /note="Tegument protein UL14"
FT /id="PRO_0000115938"
FT REGION 123..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..145
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 159 AA; 17928 MW; AAD9BAF017CE6E89 CRC64;
MLASDRRERR VRLEEAFQRE SVFKARTVEL LRGRADKKNP EFVRAFMAAK QARRDVERHL
RLAARVESVE QKARALQARV EAQAAVRGVL DRHRRFTRAD FAEALDAAED ALAAGEDRLD
DAAALDEDWA GGGAPDEDEG EEADEALLTQ WLLEEAEEA