ID   TEG3_VZVD               Reviewed;         199 AA.
AC   P09295;
DT   01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 1.
DT   23-FEB-2022, entry version 57.
DE   RecName: Full=Tegument protein UL14 homolog;
GN   ORFNames=ORF46;
OS   Varicella-zoster virus (strain Dumas) (HHV-3) (Human herpesvirus 3).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=10338;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=3018124; DOI=10.1099/0022-1317-67-9-1759;
RA   Davison A.J., Scott J.E.;
RT   "The complete DNA sequence of varicella-zoster virus.";
RL   J. Gen. Virol. 67:1759-1816(1986).
CC   -!- FUNCTION: Contributes to the nuclear transport of the viral
CC       transcriptional activator VP16 homolog during the early phase of
CC       infection. Therefore, participates indirectly in the regulation of the
CC       immediate-early gene expression. Additionally, seems to be important
CC       for efficient nuclear targeting of capsids (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250}. Host cytoplasm
CC       {ECO:0000250}. Host nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the alphaherpesvirinae HHV-1 UL14 protein
CC       family. {ECO:0000305}.
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DR   EMBL; X04370; CAA27929.1; -; Genomic_DNA.
DR   PIR; B27344; WZBE46.
DR   SMR; P09295; -.
DR   PRIDE; P09295; -.
DR   Proteomes; UP000002602; Genome.
DR   GO; GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005207; Herpes_UL14.
DR   Pfam; PF03580; Herpes_UL14; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host nucleus; Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..199
FT                   /note="Tegument protein UL14 homolog"
FT                   /id="PRO_0000115939"
FT   REGION          176..199
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   199 AA;  22545 MW;  4CAEBA102D29339B CRC64;
     MSGHTPTYAS HRRNRVKLVE AHNRAGLFKE RTLDLIRGGA SVQDPAFVYA FTAAKEACAD
     LNNQLRSAAR IASVEQKIRD IQSKVEEQTS IQQILNTNRR YIAPDFIRGL DKTEDDNTDN
     IDRLEDAVGP NIEHENHTWF GEDDEALLTQ WMLTTHPPTS KYLQLQDLCV PTTIPTDMNQ
     MQPQPISKNE NPPTPHTDV