TEG7_ALHV1
ID TEG7_ALHV1 Reviewed; 220 AA.
AC O36405;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 02-DEC-2020, entry version 47.
DE RecName: Full=Tegument protein UL51 homolog;
DE AltName: Full=Uncharacterized gene 55 protein;
GN Name=55;
OS Alcelaphine herpesvirus 1 (strain C500) (AlHV-1) (Malignant catarrhal fever
OS virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Gammaherpesvirinae; Macavirus.
OX NCBI_TaxID=654901;
OH NCBI_TaxID=9927; Connochaetes taurinus (Blue wildebeest).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=9261371; DOI=10.1128/jvi.71.9.6517-6525.1997;
RA Ensser A., Pflanz R., Fleckenstein B.;
RT "Primary structure of the alcelaphine herpesvirus 1 genome.";
RL J. Virol. 71:6517-6525(1997).
CC -!- FUNCTION: Plays several roles during the time course of infection,
CC including egress of virus particles from the perinuclear space and
CC secondary envelopment of cytoplasmic capsids that bud into specific
CC trans-Golgi network (TGN)-derived membranes.
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- SUBUNIT: Oligomerizes. Interacts with UL7 homolog; this interaction
CC mediates UL7 homolog incorporation to virions.
CC {ECO:0000250|UniProtKB:P10235, ECO:0000250|UniProtKB:P16823}.
CC -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10235}.
CC Host cytoplasm {ECO:0000250|UniProtKB:P10235}. Host Golgi apparatus
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10235}.
CC -!- PTM: Palmitoylation is necessary for Golgi localization.
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- SIMILARITY: Belongs to the herpesviridae UL51 family. {ECO:0000305}.
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DR EMBL; AF005370; AAC58102.1; -; Genomic_DNA.
DR PIR; T03150; T03150.
DR RefSeq; NP_065554.1; NC_002531.1.
DR SMR; O36405; -.
DR GeneID; 911779; -.
DR KEGG; vg:911779; -.
DR Proteomes; UP000000941; Genome.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR InterPro; IPR007619; Herpes_U44.
DR Pfam; PF04533; Herpes_U44; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host Golgi apparatus; Lipoprotein; Palmitate;
KW Phosphoprotein; Reference proteome; Virion; Virion tegument.
FT CHAIN 1..220
FT /note="Tegument protein UL51 homolog"
FT /id="PRO_0000405718"
FT LIPID 11
FT /note="S-palmitoyl cysteine; by host"
FT /evidence="ECO:0000250|UniProtKB:P10235"
SQ SEQUENCE 220 AA; 24618 MW; A909FC2A44571779 CRC64;
MASRWMEWTC CGLWLFGKPT QKKYTQLFEE PSYKCSERVK QEINKGLPPG VSVGDLILGD
KSTEALNQAH LLALQSNNIT EYLARFNAAE IPASCQGIVS NQIDKLKAMQ SVIWNAMISI
ATSNVELSDS GFQLLLDKQA CENMTLMEME KLATAISVDN TTNWAREISN IIITQPTHAL
PEAVPEKPEP IYDDPEELES TMLLQPTQQK KTTVTQQQIL