ID   TEG7_EBVG               Reviewed;         218 AA.
AC   P0CK62; P03194; Q777F4;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   02-JUN-2021, entry version 22.
DE   RecName: Full=Tegument protein UL51 homolog;
GN   ORFNames=BSRF1;
OS   Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Lymphocryptovirus.
OX   NCBI_TaxID=10376;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16306603; DOI=10.1128/jvi.79.24.15323-15330.2005;
RA   Zeng M.-S., Li D.-J., Liu Q.-L., Song L.-B., Li M.-Z., Zhang R.-H.,
RA   Yu X.-J., Wang H.-M., Ernberg I., Zeng Y.-X.;
RT   "Genomic sequence analysis of Epstein-Barr virus strain GD1 from a
RT   nasopharyngeal carcinoma patient.";
RL   J. Virol. 79:15323-15330(2005).
CC   -!- FUNCTION: Plays several roles during the time course of infection,
CC       including egress of virus particles from the perinuclear space and
CC       secondary envelopment of cytoplasmic capsids that bud into specific
CC       trans-Golgi network (TGN)-derived membranes.
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- SUBUNIT: Oligomerizes. Interacts with BBRF2; this interaction mediates
CC       BBRF2 incorporation to virions. {ECO:0000250|UniProtKB:P10235,
CC       ECO:0000250|UniProtKB:P16823}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10235}.
CC       Host cytoplasm {ECO:0000250|UniProtKB:P10235}. Host Golgi apparatus
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10235}.
CC   -!- PTM: Palmitoylation is necessary for Golgi localization.
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL51 family. {ECO:0000305}.
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DR   EMBL; AY961628; AAY41112.1; -; Genomic_DNA.
DR   RefSeq; YP_401663.1; NC_007605.1.
DR   PDB; 6LQO; X-ray; 3.09 A; H/I/J/K/L/M=34-159.
DR   PDBsum; 6LQO; -.
DR   SMR; P0CK62; -.
DR   DNASU; 3783731; -.
DR   GeneID; 3783731; -.
DR   KEGG; vg:3783731; -.
DR   Proteomes; UP000007641; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007619; Herpes_U44.
DR   Pfam; PF04533; Herpes_U44; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Host cytoplasm; Host Golgi apparatus; Lipoprotein; Palmitate;
KW   Phosphoprotein; Virion; Virion tegument.
FT   CHAIN           1..218
FT                   /note="Tegument protein UL51 homolog"
FT                   /id="PRO_0000415969"
FT   REGION          199..218
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           11
FT                   /note="S-palmitoyl cysteine; by host"
FT                   /evidence="ECO:0000250|UniProtKB:P10235"
FT   HELIX           53..89
FT                   /evidence="ECO:0007829|PDB:6LQO"
FT   HELIX           96..127
FT                   /evidence="ECO:0007829|PDB:6LQO"
SQ   SEQUENCE   218 AA;  23861 MW;  A04A22C360014A8B CRC64;
     MAFYLPDWSC CGLWLFGRPR NRYSQLPEEP ETFECPDRWR AEIDLGLPPG VQVGDLLRNE
     QTMGSLRQVY LLAVQANSIT DHLKRFDAVR VPESCRGVVE AQVAKLEAVR SVIWNTMISL
     AVSGIEMDEN GLKALLDKQA GDSLALMEME KVATALKMDE TGAWAQEISA VVSSVTAPSA
     SAPFINSAFE PEVPTPVLAP PPVVRQPEHS GPTELALT