TEG7_EHV1B
ID TEG7_EHV1B Reviewed; 245 AA.
AC P28961; Q6DLK3;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 02-JUN-2021, entry version 57.
DE RecName: Full=Tegument protein UL51 homolog;
GN OrderedLocusNames=8;
OS Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX NCBI_TaxID=31520;
OH NCBI_TaxID=9796; Equus caballus (Horse).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT "The DNA sequence of equine herpesvirus-1.";
RL Virology 189:304-316(1992).
CC -!- FUNCTION: Plays several roles during the time course of infection,
CC including egress of virus particles from the perinuclear space and
CC secondary envelopment of cytoplasmic capsids that bud into specific
CC trans-Golgi network (TGN)-derived membranes.
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- SUBUNIT: Oligomerizes. Interacts with ORF55; this interaction mediates
CC ORF55 incorporation to virions. {ECO:0000250|UniProtKB:P10235,
CC ECO:0000250|UniProtKB:P16823}.
CC -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10235}.
CC Host cytoplasm {ECO:0000250|UniProtKB:P10235}. Host Golgi apparatus
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10235}.
CC -!- PTM: Palmitoylation is necessary for Golgi localization.
CC {ECO:0000250|UniProtKB:P10235}.
CC -!- SIMILARITY: Belongs to the herpesviridae UL51 family. {ECO:0000305}.
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DR EMBL; AY665713; AAT67265.1; -; Genomic_DNA.
DR PIR; I36795; WZBEA7.
DR RefSeq; YP_053053.1; NC_001491.2.
DR SMR; P28961; -.
DR GeneID; 1487563; -.
DR KEGG; vg:1487563; -.
DR Proteomes; UP000001189; Genome.
DR GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR InterPro; IPR007625; Herpes_UL51.
DR Pfam; PF04540; Herpes_UL51; 1.
PE 3: Inferred from homology;
KW Host cytoplasm; Host Golgi apparatus; Lipoprotein; Palmitate;
KW Phosphoprotein; Reference proteome; Virion; Virion tegument.
FT CHAIN 1..245
FT /note="Tegument protein UL51 homolog"
FT /id="PRO_0000116100"
FT REGION 225..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 230..245
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT LIPID 10
FT /note="S-palmitoyl cysteine; by host"
FT /evidence="ECO:0000250|UniProtKB:P10235"
SQ SEQUENCE 245 AA; 26365 MW; 2D5BC04A882492A5 CRC64;
MFKWLMSSLC GIRNSTSPEV YEPIIGGQNP ATMLRLQSAL AAVNALLPAT LTIEDVISSA
DNTRRLVKAQ TLARTYQACQ HNIECLSRHR ASSDNPNLNA VVTTHMINAK RLSDTCLAAL
MHLYLSVGAV DATTDTMVDH AIRMTAENSV VMADVAVLEK TLGLDPQATV RAQDLLALNS
GVLNSVNAVA EMTDPTDDVE FTQSVHSPLL PRQLSTTEVV GVPSPVKSNL KSKHKPKRKA
SLVAV