ID   TEG7_EHV2               Reviewed;         224 AA.
AC   Q66657;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 53.
DE   RecName: Full=Tegument protein UL51 homolog;
GN   Name=55;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
CC   -!- FUNCTION: Plays several roles during the time course of infection,
CC       including egress of virus particles from the perinuclear space and
CC       secondary envelopment of cytoplasmic capsids that bud into specific
CC       trans-Golgi network (TGN)-derived membranes.
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- SUBUNIT: Oligomerizes. Interacts with UL7 homolog; this interaction
CC       mediates UL7 homolog incorporation to virions.
CC       {ECO:0000250|UniProtKB:P10235, ECO:0000250|UniProtKB:P16823}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10235}.
CC       Host cytoplasm {ECO:0000250|UniProtKB:P10235}. Host Golgi apparatus
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10235}.
CC   -!- PTM: Palmitoylation is necessary for Golgi localization.
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL51 family. {ECO:0000305}.
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DR   EMBL; U20824; AAC13843.1; -; Genomic_DNA.
DR   PIR; S55650; S55650.
DR   RefSeq; NP_042652.1; NC_001650.2.
DR   SMR; Q66657; -.
DR   GeneID; 1461068; -.
DR   KEGG; vg:1461068; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007619; Herpes_U44.
DR   Pfam; PF04533; Herpes_U44; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host Golgi apparatus; Lipoprotein; Palmitate;
KW   Phosphoprotein; Reference proteome; Virion; Virion tegument.
FT   CHAIN           1..224
FT                   /note="Tegument protein UL51 homolog"
FT                   /id="PRO_0000406067"
FT   REGION          188..224
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   LIPID           11
FT                   /note="S-palmitoyl cysteine; by host"
FT                   /evidence="ECO:0000250|UniProtKB:P10235"
SQ   SEQUENCE   224 AA;  24682 MW;  2EA9DB95859230B4 CRC64;
     MSSRWIQWTC CGLWPFGKSS RQYRQIINVY EDDSERVRAE IDMGLPPGVS VGDLLQNRQG
     EEAIRQAHML ALQSNAITDY LQRFDSVRVP ESCQSIVSAQ IAKLRSVQHI IWNTMISMAV
     GNVTIDDSTL KVLLNKQAGE SMALMEMEKL AAALKMDGST DWAQNIASVV TAPPRAAREQ
     MAFREPIYDD PEGGMEMIDL SSTPGPTPAP TPAPSMERVA VPAS