ID   TEG7_EHV4               Reviewed;         244 AA.
AC   Q00038;
DT   01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-1992, sequence version 1.
DT   02-DEC-2020, entry version 40.
DE   RecName: Full=Tegument protein UL51 homolog;
GN   Name=8; Synonyms=B2;
OS   Equine herpesvirus 4 (strain 1942) (EHV-4) (Equine rhinopneumonitis virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX   NCBI_TaxID=10333;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1850013; DOI=10.1128/jvi.65.5.2320-2326.1991;
RA   Whittaker G.R., Riggio M.P., Halliburton I.W., Killington R.A., Allen G.P.,
RA   Meredith D.M.;
RT   "Antigenic and protein sequence homology between VP13/14, a herpes simplex
RT   virus type 1 tegument protein, and gp10, a glycoprotein of equine
RT   herpesvirus 1 and 4.";
RL   J. Virol. 65:2320-2326(1991).
CC   -!- FUNCTION: Plays several roles during the time course of infection,
CC       including egress of virus particles from the perinuclear space and
CC       secondary envelopment of cytoplasmic capsids that bud into specific
CC       trans-Golgi network (TGN)-derived membranes.
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- SUBUNIT: Oligomerizes. Interacts with ORF55; this interaction mediates
CC       ORF55 incorporation to virions. {ECO:0000250|UniProtKB:P10235,
CC       ECO:0000250|UniProtKB:P16823}.
CC   -!- SUBCELLULAR LOCATION: Virion tegument {ECO:0000250|UniProtKB:P10235}.
CC       Host cytoplasm {ECO:0000250|UniProtKB:P10235}. Host Golgi apparatus
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- PTM: Phosphorylated. {ECO:0000250|UniProtKB:P10235}.
CC   -!- PTM: Palmitoylation is necessary for Golgi localization.
CC       {ECO:0000250|UniProtKB:P10235}.
CC   -!- SIMILARITY: Belongs to the herpesviridae UL51 family. {ECO:0000305}.
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DR   EMBL; X17684; CAA35668.1; -; Genomic_DNA.
DR   PIR; S36703; S36703.
DR   RefSeq; NP_045225.1; NC_001844.1.
DR   SMR; Q00038; -.
DR   GeneID; 1487646; -.
DR   KEGG; vg:1487646; -.
DR   GO; GO:0044177; C:host cell Golgi apparatus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019033; C:viral tegument; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007625; Herpes_UL51.
DR   Pfam; PF04540; Herpes_UL51; 1.
PE   3: Inferred from homology;
KW   Host cytoplasm; Host Golgi apparatus; Lipoprotein; Palmitate;
KW   Phosphoprotein; Virion; Virion tegument.
FT   CHAIN           1..244
FT                   /note="Tegument protein UL51 homolog"
FT                   /id="PRO_0000116101"
FT   LIPID           10
FT                   /note="S-palmitoyl cysteine; by host"
FT                   /evidence="ECO:0000250|UniProtKB:P10235"
SQ   SEQUENCE   244 AA;  26238 MW;  3F250DFA3D4BDFFE CRC64;
     MFKWLMSSLC GTKNPASLEE VYEPIMGGKN PATMLRLQSA LAAVNALLPA TLTIEDVISS
     ADNTRRLVKA QTLARTYQAC QHNIECLSRH RASSDNPNLN AVVATHMANA KRLSDTCLAA
     LMHLYLSVGA VDATTDTMVD HAIRMTAENS VVMADVAVLE KTLGLEPQPS VMAHDLLALE
     SSVYNSGNSV PVNDYPAEDV ESTQSVHSPL LSKRPSNTEV VCSSIPVKSN LKSKPRRKPS
     LVAA