ID   TEGU_HCMV               Reviewed;         549 AA.
AC   P07387;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   23-FEB-2022, entry version 35.
DE   RecName: Full=Tegument protein;
DE   AltName: Full=67 kDa phosphorylated protein;
OS   Human cytomegalovirus (HHV-5) (Human herpesvirus 5).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Cytomegalovirus.
OX   NCBI_TaxID=10359;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2993668; DOI=10.1128/jvi.56.1.7-11.1985;
RA   Davis M.G., Huang E.-S.;
RT   "Nucleotide sequence of a human cytomegalovirus DNA fragment encoding a 67-
RT   kilodalton phosphorylated viral protein.";
RL   J. Virol. 56:7-11(1985).
CC   -!- FUNCTION: This viral structural protein may have important functions,
CC       such as protein kinase activity, DNA binding, and possible
CC       transcriptional activation of immediate-early genes.
CC   -!- MISCELLANEOUS: The tegument is a granular zone surrounding the capsid.
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DR   EMBL; M11911; AAA45986.1; -; Genomic_DNA.
DR   PIR; A25316; TEBEHC.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   DNA-binding; Phosphoprotein.
FT   CHAIN           1..549
FT                   /note="Tegument protein"
FT                   /id="PRO_0000115245"
FT   REGION          50..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          353..391
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          523..542
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        66..90
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        355..370
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..538
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   549 AA;  61578 MW;  50C1E5692F632E14 CRC64;
     MCRIRTFRLR RKRRVSGRSF CRSRIDPGYV RERPYIGGRS RPTTFHLTRK KKAPLGGDLS
     PSFARSPVLE PSSPPQALSV PSLSSEKKTA SPTCVKHHLS GGAVRRANTV VPRTKKRTSR
     HHTLMSTTCR CWSSSIVLYE HLDARVSDVG KTSRRRRCSL GGTLSGSIIS IVAKRDCDYD
     EPHHLFFMLL LYKRLMSTTL GISHLVKHAR FSSLQGTLGS LKGTVYRPKQ KTHTCNRSTT
     SNDTKTQSYN ALFMERTWNK KTIAARAKPK PSGEAGASFP TQSLGSLSSF FFPDSLKNHR
     HSPMTRNQLL EHKRSQQVET NKLDDAITLY CVYIDRCEFV GKKRRCMMHN DRETGDCSSL
     PNANTQTHRF PSPHKEMRPP PTNEADSCSS YDGALARRAS SPLREGTSGS SAHRPKQQCL
     LHCHQSISCI LFPPNSSPQH QFALLRKVVA TAAAATGRSS SPRPQTLYMC RKCVNTCYCP
     MRLVHRYMFQ NLLIHLRAHR LGVSSSSNWP TFSTTVVNPC TTTPIKTTSS SSPRPRNDTR
     SPPILGMCF