ID   TEG_PRIM2               Reviewed;         318 AA.
AC   P30420;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 52.
DE   RecName: Full=Protein teg;
DE            EC=3.1.1.-;
GN   Name=teg;
OS   Priestia megaterium (strain ATCC 14581 / DSM 32 / CCUG 1817 / JCM 2506 /
OS   NBRC 15308 / NCIMB 9376 / NCTC 10342 / NRRL B-14308 / VKM B-512 / Ford 19)
OS   (Bacillus megaterium).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Priestia.
OX   NCBI_TaxID=1348623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 14581 / DSM 32 / CCUG 1817 / JCM 2506 / NBRC 15308 / NCIMB 9376
RC   / NCTC 10342 / NRRL B-14308 / VKM B-512 / Ford 19;
RA   Temann U.A.;
RL   Submitted (MAY-1990) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable lipid hydrolase. {ECO:0000250}.
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DR   EMBL; X53048; CAA37216.1; -; Genomic_DNA.
DR   PIR; S24923; S24923.
DR   AlphaFoldDB; P30420; -.
DR   SMR; P30420; -.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002641; PNPLA_dom.
DR   Pfam; PF01734; Patatin; 1.
DR   SUPFAM; SSF52151; SSF52151; 1.
DR   PROSITE; PS51635; PNPLA; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Lipid degradation; Lipid metabolism.
FT   CHAIN           1..318
FT                   /note="Protein teg"
FT                   /id="PRO_0000072478"
FT   DOMAIN          7..182
FT                   /note="PNPLA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   MOTIF           11..16
FT                   /note="GXGXXG"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   MOTIF           42..46
FT                   /note="GXSXG"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   ACT_SITE        44
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
FT   ACT_SITE        169
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01161"
SQ   SEQUENCE   318 AA;  35263 MW;  2B85DCC3C4668EDD CRC64;
     MTKYRIITFD GGGTLGALSL QLLNRLAYQN PKLISETNVF SGNSIGSFTA LALASGRSPE
     ETFDFFKDQI LPAFSVSRPG GPVFNQQVPY SGLIKAIRTF FPRDLRLRDL KKRIVVPAFH
     LFAPELNRWN PVLFHNFLGS PYLNEKASDV ILRSSAAPAT QRAYQNYVDG YTVATNTSTA
     SIAFAVGKAK QPLDQIAVLS IGTGEQPTQL RRDTKGWGMV SADNILPEDM EDLPPNWGVL
     LDRSPNEPLL PFLQIISGGS SYYESMVSSE LLGDQFFRLN PRIPNFSKTD PSVVPALISI
     ANKTNLRPAF QFIERNWN