ID   TEKT1_RAT               Reviewed;         418 AA.
AC   Q99JD2;
DT   08-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=Tektin-1;
GN   Name=Tekt1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Sprague-Dawley; TISSUE=Testis;
RA   Hurd E., Frayne J., Hall L.;
RT   "Sequence and developmental expression of tektin transcripts in rat
RT   testis.";
RL   Submitted (MAR-2001) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Brown Norway; TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms
CC       filamentous polymers in the walls of ciliary and flagellar
CC       microtubules. {ECO:0000250|UniProtKB:Q32KZ9}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:Q32KZ9}. Cytoplasm, cytoskeleton, flagellum
CC       axoneme {ECO:0000250|UniProtKB:Q32KZ9}.
CC   -!- TISSUE SPECIFICITY: Predominantly expressed in testis.
CC   -!- SIMILARITY: Belongs to the tektin family. {ECO:0000305}.
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DR   EMBL; AJ306427; CAC34480.1; -; mRNA.
DR   EMBL; BC078773; AAH78773.1; -; mRNA.
DR   RefSeq; NP_445960.1; NM_053508.2.
DR   AlphaFoldDB; Q99JD2; -.
DR   SMR; Q99JD2; -.
DR   STRING; 10116.ENSRNOP00000062126; -.
DR   iPTMnet; Q99JD2; -.
DR   PhosphoSitePlus; Q99JD2; -.
DR   PaxDb; Q99JD2; -.
DR   PRIDE; Q99JD2; -.
DR   Ensembl; ENSRNOT00000066740; ENSRNOP00000062126; ENSRNOG00000014973.
DR   GeneID; 85270; -.
DR   KEGG; rno:85270; -.
DR   CTD; 83659; -.
DR   RGD; 619913; Tekt1.
DR   eggNOG; KOG2685; Eukaryota.
DR   GeneTree; ENSGT00950000182894; -.
DR   HOGENOM; CLU_033588_2_2_1; -.
DR   InParanoid; Q99JD2; -.
DR   OMA; EPLHITQ; -.
DR   OrthoDB; 581072at2759; -.
DR   PRO; PR:Q99JD2; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000014973; Expressed in testis and 14 other tissues.
DR   Genevisible; Q99JD2; RN.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   GO; GO:0015630; C:microtubule cytoskeleton; ISO:RGD.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR   GO; GO:0060271; P:cilium assembly; IBA:GO_Central.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IBA:GO_Central.
DR   InterPro; IPR000435; Tektin.
DR   PANTHER; PTHR19960; PTHR19960; 1.
DR   PRINTS; PR00511; TEKTIN.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Coiled coil; Cytoplasm; Cytoskeleton; Flagellum;
KW   Microtubule; Reference proteome.
FT   CHAIN           1..418
FT                   /note="Tektin-1"
FT                   /id="PRO_0000184564"
FT   COILED          20..107
FT                   /evidence="ECO:0000255"
FT   COILED          134..177
FT                   /evidence="ECO:0000255"
FT   COILED          266..308
FT                   /evidence="ECO:0000255"
FT   COILED          332..383
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   418 AA;  48591 MW;  6B8D83A05D912DB1 CRC64;
     MAKLLQSPPK FLPAEWYIAN KSQYHRAEAQ RSRSERLVAE SQRLVEEIEK TTRKSQSDVN
     KKLEQRLEEV KFWKKELDDK LEHLVNETED LLTYKIRLER SLESYKEPLH ITEKCLAYRE
     KRVGIDLVHD VVDQELQKEA DIIHGVMNLL TRTVEEATEQ IRLNRSAKYN LEKDLKDKFT
     AITIDDICFS LNNNSPDIKY SENVVRIEPN SVSLEDWLDF SNTNMQKADK QLNNSMALKT
     LVDQILSQTA NDLRRQCEVV DTAFVNGLKE TKDARNKLAD HLAKVMDEIA SQEKNIEVLE
     NAITQQEGPA KVAHTRLENR TYRPNVELCR DVAQYRLIRE VQEIKHNVAR LEETLAQAQI
     QLKALFRRQL ALQEEIQVKE NTIYIDQVLC MEMRKSIPPR DGDDHGAWEG GIRAEAIC