ID   TEKT4_XENLA             Reviewed;         446 AA.
AC   Q5PPV2;
DT   28-NOV-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-JAN-2005, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Tektin-4;
GN   Name=tekt4;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Microtubule inner protein (MIP) part of the dynein-decorated
CC       doublet microtubules (DMTs) in cilia and flagellar axoneme. Forms
CC       filamentous polymers in the walls of ciliary and flagellar microtubules
CC       (By similarity). Contributes to normal sperm motility (By similarity).
CC       {ECO:0000250|UniProtKB:Q2TA38, ECO:0000250|UniProtKB:Q6X6Z7}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:Q2TA38}. Cell projection, cilium, flagellum
CC       {ECO:0000250|UniProtKB:Q149S1}. Note=Found in the abaxial (convex)
CC       surface of outer dense fibers in sperm flagella.
CC       {ECO:0000250|UniProtKB:Q149S1}.
CC   -!- SIMILARITY: Belongs to the tektin family. {ECO:0000305}.
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DR   EMBL; BC087484; AAH87484.1; -; mRNA.
DR   RefSeq; NP_001088802.1; NM_001095333.1.
DR   AlphaFoldDB; Q5PPV2; -.
DR   SMR; Q5PPV2; -.
DR   DNASU; 496070; -.
DR   GeneID; 496070; -.
DR   KEGG; xla:496070; -.
DR   CTD; 496070; -.
DR   Xenbase; XB-GENE-5848490; tekt4.S.
DR   OrthoDB; 581072at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10S.
DR   Bgee; 496070; Expressed in testis and 16 other tissues.
DR   GO; GO:0005879; C:axonemal microtubule; ISS:UniProtKB.
DR   GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
DR   GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
DR   GO; GO:0060294; P:cilium movement involved in cell motility; IEA:InterPro.
DR   InterPro; IPR000435; Tektin.
DR   PANTHER; PTHR19960; PTHR19960; 1.
DR   PRINTS; PR00511; TEKTIN.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cilium biogenesis/degradation; Coiled coil;
KW   Cytoplasm; Cytoskeleton; Flagellum; Reference proteome.
FT   CHAIN           1..446
FT                   /note="Tektin-4"
FT                   /id="PRO_0000261165"
FT   COILED          182..215
FT                   /evidence="ECO:0000255"
FT   COILED          297..346
FT                   /evidence="ECO:0000255"
FT   COILED          378..422
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   446 AA;  51313 MW;  42808C1EE0D29A07 CRC64;
     MNSQVLVSRP LAPQSVPAVS LPVQSAQVAQ NTGPHSSSGL ATAGFRTAKY LHEEWQQGNL
     TTFYQAFSDR DQSEKGRHES KQLVAETEAR AQRSQADCTK SLGERLLDIH FWKSELSREI
     RDVGAETQLL VQQKVRLERA LDATDIPFTI ATDNLKCRDR RRGSELVRDD VEMQLLKEVD
     LIRNVQELLK RTLDQAAQQI RQNRDAKEAL EMDYSDKAEA YEFDDKCGRY NNQSTDIQFH
     LNSSKYEDNT STPESWAQYT HENIYKAERE RMASINLRSL IDSILQDISE DLQAQFDAIA
     VDFEKRCREL EDAKQKLEMH LKKTLEEIGG QEKNIAALKQ AINDKSPPLK VAQTRLHERS
     YRPNVELCRD HVQIRLVSEV GELTDSFDAL KLKLEESEQS LRNLEDTRMS LEKDIANKAN
     SIFIDREKCM THRTRYPHGM KLLGYQ