ID   TEMPT_APLCA             Reviewed;         125 AA.
AC   Q7Z0T3;
DT   04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 34.
DE   RecName: Full=Temptin;
DE   Flags: Precursor;
OS   Aplysia californica (California sea hare).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Tectipleura; Aplysiida; Aplysioidea;
OC   Aplysiidae; Aplysia.
OX   NCBI_TaxID=6500;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 23-28; 73-77 AND 89-93,
RP   FUNCTION, TISSUE SPECIFICITY, AND INTERACTION WITH ATTRACTIN AND ENTICIN.
RC   TISSUE=Albumen gland;
RX   PubMed=15054104; DOI=10.1074/jbc.m313585200;
RA   Cummins S.F., Nichols A.E., Amare A., Hummon A.B., Sweedler J.V.,
RA   Nagle G.T.;
RT   "Characterization of Aplysia enticin and temptin, two novel water-borne
RT   protein pheromones that act in concert with attractin to stimulate mate
RT   attraction.";
RL   J. Biol. Chem. 279:25614-25622(2004).
RN   [2]
RP   PROTEIN SEQUENCE, CIRCULAR DICHROISM ANALYSIS, DISULFIDE BONDS, FUNCTION,
RP   AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=17894821; DOI=10.1111/j.1742-4658.2007.06070.x;
RA   Cummins S.F., Xie F., de Vries M.R., Annangudi S.P., Misra M., Degnan B.M.,
RA   Sweedler J.V., Nagle G.T., Schein C.H.;
RT   "Aplysia temptin -- the 'glue' in the water-borne attractin pheromone
RT   complex.";
RL   FEBS J. 274:5425-5437(2007).
CC   -!- FUNCTION: A component of the complex of water-borne protein pheromones
CC       that stimulates attraction and mating behavior. Modulates pheromone
CC       signaling by direct binding to attractin. {ECO:0000269|PubMed:15054104,
CC       ECO:0000269|PubMed:17894821}.
CC   -!- SUBUNIT: Binds to attractin and enticin.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Produced by the albumen gland of the egg cordons.
CC       {ECO:0000269|PubMed:15054104}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AY309079; AAP73787.1; -; mRNA.
DR   RefSeq; NP_001191545.1; NM_001204616.1.
DR   AlphaFoldDB; Q7Z0T3; -.
DR   GeneID; 100533318; -.
DR   OrthoDB; 1493133at2759; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005186; F:pheromone activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Disulfide bond; Pheromone; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000269|PubMed:15054104"
FT   CHAIN           23..125
FT                   /note="Temptin"
FT                   /id="PRO_0000311913"
FT   REGION          78..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        40..125
FT                   /evidence="ECO:0000269|PubMed:17894821"
FT   DISULFID        79..99
FT                   /evidence="ECO:0000269|PubMed:17894821"
SQ   SEQUENCE   125 AA;  13320 MW;  F1AC10863C22842C CRC64;
     MEQKRTLRVF LAVSLLCALA NAYPQYQAVI PNGSSVPNPC NTSQIAQGVG HINFQGTGPL
     NPFGEDFKAA GKQWTTDLCD MDSDGDGRSN GVELGDPECV WSQGETPART TDLSHPGFDE
     ATVSC