TEPP_MOUSE
ID TEPP_MOUSE Reviewed; 216 AA.
AC Q6IMH0; Q3SXB6; Q9D9K7;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Testis, prostate and placenta-expressed protein;
GN Name=Tepp;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION.
RX PubMed=14652002; DOI=10.1016/j.bbrc.2003.11.031;
RA Bera T.K., Hahn Y., Lee B., Pastan I.H.;
RT "TEPP, a new gene specifically expressed in testis, prostate, and placenta
RT and well conserved in chordates.";
RL Biochem. Biophys. Res. Commun. 312:1209-1215(2003).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q6IMH0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q6IMH0-2; Sequence=VSP_032404;
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK006802; BAB24747.1; -; mRNA.
DR EMBL; BC087870; AAH87870.1; -; mRNA.
DR EMBL; BC104382; AAI04383.1; -; mRNA.
DR EMBL; BC104383; AAI04384.1; -; mRNA.
DR EMBL; BK001511; DAA01955.1; -; mRNA.
DR CCDS; CCDS22557.1; -. [Q6IMH0-1]
DR CCDS; CCDS22558.1; -. [Q6IMH0-2]
DR RefSeq; NP_082808.1; NM_028532.3. [Q6IMH0-2]
DR RefSeq; NP_955534.1; NM_199455.2. [Q6IMH0-1]
DR AlphaFoldDB; Q6IMH0; -.
DR STRING; 10090.ENSMUSP00000125362; -.
DR iPTMnet; Q6IMH0; -.
DR PhosphoSitePlus; Q6IMH0; -.
DR PaxDb; Q6IMH0; -.
DR PRIDE; Q6IMH0; -.
DR ProteomicsDB; 263103; -. [Q6IMH0-1]
DR ProteomicsDB; 263104; -. [Q6IMH0-2]
DR Antibodypedia; 62568; 4 antibodies from 4 providers.
DR DNASU; 73407; -.
DR Ensembl; ENSMUST00000098480; ENSMUSP00000096080; ENSMUSG00000090206. [Q6IMH0-2]
DR Ensembl; ENSMUST00000161029; ENSMUSP00000125362; ENSMUSG00000090206. [Q6IMH0-1]
DR GeneID; 73407; -.
DR KEGG; mmu:73407; -.
DR UCSC; uc009myd.2; mouse. [Q6IMH0-1]
DR UCSC; uc009mye.2; mouse. [Q6IMH0-2]
DR CTD; 374739; -.
DR MGI; MGI:1920657; Tepp.
DR VEuPathDB; HostDB:ENSMUSG00000090206; -.
DR eggNOG; ENOG502R4EY; Eukaryota.
DR GeneTree; ENSGT00390000013928; -.
DR HOGENOM; CLU_2249207_0_0_1; -.
DR InParanoid; Q6IMH0; -.
DR OMA; PPQYCLN; -.
DR OrthoDB; 1113022at2759; -.
DR PhylomeDB; Q6IMH0; -.
DR TreeFam; TF329060; -.
DR BioGRID-ORCS; 73407; 1 hit in 68 CRISPR screens.
DR PRO; PR:Q6IMH0; -.
DR Proteomes; UP000000589; Chromosome 8.
DR RNAct; Q6IMH0; protein.
DR Bgee; ENSMUSG00000090206; Expressed in seminiferous tubule of testis and 35 other tissues.
DR ExpressionAtlas; Q6IMH0; baseline and differential.
DR Genevisible; Q6IMH0; MM.
DR InterPro; IPR034584; TEPP.
DR PANTHER; PTHR35348; PTHR35348; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..216
FT /note="Testis, prostate and placenta-expressed protein"
FT /id="PRO_0000325778"
FT VAR_SEQ 1..112
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:15489334,
FT ECO:0000303|PubMed:16141072"
FT /id="VSP_032404"
FT CONFLICT 142
FT /note="S -> F (in Ref. 2; AAI04383)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 216 AA; 24949 MW; 3DEFAA2AEFA07671 CRC64;
MAQIIDLVPW DECSAHLYAS PAVLLPLERV RHPLAGVKHQ LYHPALPSLR RMDMDTVKGC
LSDEHCQSST YFSKDDFNKA HFTLLGVPNK PLQCLDFTAT GQKLCHKYRG GKMIPIAPGI
NRVDWPCFTR AIEDWSKFVS RSEEFKLPCA NKRVEGFSGY AVRYLKPEVT QNWRYCLNQN
PSLDRYGQKP LPFDSLNAFR RFGSHYSRIN YLTPWH
