ID   TERB2_DANRE             Reviewed;         212 AA.
AC   Q5BJD2;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Telomere repeats-binding bouquet formation protein 2 {ECO:0000250|UniProtKB:Q9D494};
GN   Name=terb2 {ECO:0000250|UniProtKB:Q9D494};
GN   ORFNames=zgc:111992 {ECO:0000303|Ref.1};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Olfactory epithelium;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Meiosis-specific telomere-associated protein involved in
CC       meiotic telomere attachment to the nucleus inner membrane, a crucial
CC       step for homologous pairing and synapsis. Component of the MAJIN-TERB1-
CC       TERB2 complex, which promotes telomere cap exchange by mediating
CC       attachment of telomeric DNA to the inner nuclear membrane and
CC       replacement of the protective cap of telomeric chromosomes: in early
CC       meiosis, the MAJIN-TERB1-TERB2 complex associates with telomeric DNA
CC       and the shelterin/telosome complex. During prophase, the complex
CC       matures and promotes release of the shelterin/telosome complex from
CC       telomeric DNA. {ECO:0000250|UniProtKB:Q9D494}.
CC   -!- SUBUNIT: Component of the MAJIN-TERB1-TERB2 complex.
CC       {ECO:0000250|UniProtKB:Q9D494}.
CC   -!- SIMILARITY: Belongs to the TERB2 family. {ECO:0000305}.
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DR   EMBL; BC091528; AAH91528.1; -; mRNA.
DR   RefSeq; NP_001013486.1; NM_001013468.1.
DR   AlphaFoldDB; Q5BJD2; -.
DR   SMR; Q5BJD2; -.
DR   STRING; 7955.ENSDARP00000057676; -.
DR   PaxDb; Q5BJD2; -.
DR   DNASU; 541341; -.
DR   GeneID; 541341; -.
DR   KEGG; dre:541341; -.
DR   CTD; 145645; -.
DR   ZFIN; ZDB-GENE-050320-30; terb2.
DR   eggNOG; ENOG502S1BT; Eukaryota.
DR   InParanoid; Q5BJD2; -.
DR   OrthoDB; 1206947at2759; -.
DR   PhylomeDB; Q5BJD2; -.
DR   PRO; PR:Q5BJD2; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Unplaced.
DR   GO; GO:0000781; C:chromosome, telomeric region; ISS:UniProtKB.
DR   GO; GO:0005637; C:nuclear inner membrane; ISS:UniProtKB.
DR   GO; GO:0007129; P:homologous chromosome pairing at meiosis; ISS:UniProtKB.
DR   GO; GO:0070197; P:meiotic attachment of telomere to nuclear envelope; ISS:UniProtKB.
DR   GO; GO:0045141; P:meiotic telomere clustering; ISS:UniProtKB.
DR   InterPro; IPR028065; TERB2.
DR   PANTHER; PTHR35345; PTHR35345; 1.
DR   Pfam; PF15101; TERB2; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..212
FT                   /note="Telomere repeats-binding bouquet formation protein
FT                   2"
FT                   /id="PRO_0000263719"
SQ   SEQUENCE   212 AA;  24285 MW;  183C610992F86B7E CRC64;
     MFKRKTAWFS DSVEKEVISF WVSEGGDISS WKTAGYLFSD DASSEDTKRI YGSEDYVKNR
     ATVFHSSFLL ACQPRQSVTS VPIGHYVLPP DFVQNEMKAI IGRFIWEKDE QVICEEQINP
     EVPKDILSGE TEDHALRERS SQDDYQTVTS QSKVCSCCEM RQYPVNNMIS GYVHIDQMRK
     YSGELKDFLP SLHGHDVSRS NDPTPPFHRK AV