ID   TERC_SERMA              Reviewed;         346 AA.
AC   Q52356;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Tellurium resistance protein TerC;
GN   Name=terC;
OS   Serratia marcescens.
OG   Plasmid IncHI2 R478.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Serratia.
OX   NCBI_TaxID=615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7665479; DOI=10.1128/jb.177.17.5016-5027.1995;
RA   Whelan K.F., Colleran E., Taylor D.E.;
RT   "Phage inhibition, colicin resistance, and tellurite resistance are encoded
RT   by a single cluster of genes on the IncHI2 plasmid R478.";
RL   J. Bacteriol. 177:5016-5027(1995).
CC   -!- FUNCTION: Could conceivably alter the intracellular level of tellurium
CC       in a manner leading to resistance. Alternatively its presence in the
CC       membrane may provide a barrier to entry of the tellurium ions.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the TerC family. {ECO:0000305}.
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DR   EMBL; U59239; AAA86849.1; -; Genomic_DNA.
DR   RefSeq; NP_941152.1; NC_005211.1.
DR   RefSeq; WP_000255079.1; NZ_VOMJ01000014.1.
DR   AlphaFoldDB; Q52356; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046690; P:response to tellurium ion; IEA:UniProtKB-KW.
DR   InterPro; IPR005496; Integral_membrane_TerC.
DR   InterPro; IPR022369; Integral_membrane_TerC_rswitch.
DR   PANTHER; PTHR30238:SF0; PTHR30238:SF0; 1.
DR   Pfam; PF03741; TerC; 1.
DR   TIGRFAMs; TIGR03718; R_switched_Alx; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Plasmid; Tellurium resistance; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..346
FT                   /note="Tellurium resistance protein TerC"
FT                   /id="PRO_0000103409"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        132..152
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        227..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        252..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        316..336
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   346 AA;  38393 MW;  D80842755CF892DA CRC64;
     MVSTHIGFPT ETVIVFIALS VGAIFIDLFM HRDDKPISLK SAALWSVFWV VVAMAFAGFL
     YIHHGAEVAS LFVTGYALEK VLSVDNLFVM MAIFSWFAVP DRYRHRVLYW GIIGAIVFRG
     IFVAIGTSLL SLGPYVEVVF AIIVAWTAVM MLKSGDDDDE IEDYSQHLAY RMVKRFFPIW
     PKLRGHAFLL NQKEVDAELA KPENSDVTIG RGKKAALYAT PLFLCVAVVE LSDVMFAFDS
     VPAIIAVSRE PLIVYSAMMF AILGLRTLYF VLEALKQYLV HLEKAVIVLL FFIAAKLGLN
     ATDHIWHHGY SIAATTSLYV VLGVLALGIL ASVMFPGKPE SEEKGS