TERM_DROME
ID TERM_DROME Reviewed; 428 AA.
AC P11455; Q9VVQ3;
DT 01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 2.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Protein terminus;
GN Name=term; Synonyms=ter; ORFNames=CG4216;
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=3334721; DOI=10.1016/0012-1606(88)90061-9;
RA Baldarelli R.M., Mahoney P.A., Salas F., Gustavson E., Boyer P.D.,
RA Chang M.-F., Roark M., Lengyel J.A.;
RT "Transcripts of the Drosophila blastoderm-specific locus, terminus, are
RT concentrated posteriorly and encode a potential DNA-binding finger.";
RL Dev. Biol. 125:85-95(1988).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC -!- DEVELOPMENTAL STAGE: Expressed from the cellular blastoderm stage on,
CC most during gastrulation and is no longer detected by the end of germ
CC band extension.
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DR EMBL; M19140; AAA28928.1; -; mRNA.
DR EMBL; AE014296; AAF49257.1; -; Genomic_DNA.
DR PIR; A43741; A43741.
DR RefSeq; NP_524882.2; NM_080143.4.
DR AlphaFoldDB; P11455; -.
DR BioGRID; 70682; 38.
DR DIP; DIP-17145N; -.
DR IntAct; P11455; 7.
DR STRING; 7227.FBpp0074878; -.
DR PaxDb; P11455; -.
DR PRIDE; P11455; -.
DR DNASU; 47208; -.
DR EnsemblMetazoa; FBtr0075112; FBpp0074878; FBgn0003683.
DR GeneID; 47208; -.
DR KEGG; dme:Dmel_CG4216; -.
DR UCSC; CG4216-RA; d. melanogaster.
DR CTD; 47208; -.
DR FlyBase; FBgn0003683; term.
DR VEuPathDB; VectorBase:FBgn0003683; -.
DR eggNOG; ENOG502T9CR; Eukaryota.
DR HOGENOM; CLU_772264_0_0_1; -.
DR InParanoid; P11455; -.
DR OMA; LHIHQQL; -.
DR OrthoDB; 1076108at2759; -.
DR PhylomeDB; P11455; -.
DR SignaLink; P11455; -.
DR BioGRID-ORCS; 47208; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 47208; -.
DR PRO; PR:P11455; -.
DR Proteomes; UP000000803; Chromosome 3L.
DR Bgee; FBgn0003683; Expressed in ectoderm and 19 other tissues.
DR Genevisible; P11455; DM.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR013087; Znf_C2H2_type.
PE 2: Evidence at transcript level;
KW Developmental protein; DNA-binding; Metal-binding; Reference proteome;
KW Zinc; Zinc-finger.
FT CHAIN 1..428
FT /note="Protein terminus"
FT /id="PRO_0000072487"
FT ZN_FING 325..346
FT /note="C3H1-type"
FT CONFLICT 144
FT /note="A -> V (in Ref. 1; AAA28928)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 428 AA; 49166 MW; F545653F738AE434 CRC64;
MFDEPIISSF VFTNEETTQT FHHQWFSQGQ LHECATCYSS IDADEPPSQH WLRGGEASQG
LHLTKQQQAV MDIIEARQIE TFFFCDESSK DKLEHFMGET CARGIPELLR WMFQNNTVAV
EFNLACYVNA MDQVLIFQSG SLRADHHYDV DESVGVVYEM LMQRIENYLN CSSEYGMAEC
SITRLKVQVK RIRVEADGQS ADSSVFALPL QLQEEEGLTA TTGCSTSEAE LASLRSAYLK
HFRECNGYFP PNMRVNLYGL QQCKTTKELY VVPYHISETL QQLPNKNFLI LNNIMGQFQR
LHELSTPVNS IERDQTSSPL KDLHCRRCRT QFSRRSKLHI HQKLRCGQDF SVDSMHADIV
EIYEQCLPIS RSVFQHACYG ITKPKTMMRK GQFVPIECDW RSESSVKVQH GPCVVISNAQ
HNSPCKFY