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TERM_DROME
ID   TERM_DROME              Reviewed;         428 AA.
AC   P11455; Q9VVQ3;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 2.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Protein terminus;
GN   Name=term; Synonyms=ter; ORFNames=CG4216;
OS   Drosophila melanogaster (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7227;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=3334721; DOI=10.1016/0012-1606(88)90061-9;
RA   Baldarelli R.M., Mahoney P.A., Salas F., Gustavson E., Boyer P.D.,
RA   Chang M.-F., Roark M., Lengyel J.A.;
RT   "Transcripts of the Drosophila blastoderm-specific locus, terminus, are
RT   concentrated posteriorly and encode a potential DNA-binding finger.";
RL   Dev. Biol. 125:85-95(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Berkeley;
RX   PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA   Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA   Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA   George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA   Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA   Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA   Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA   An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA   Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA   Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA   Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA   Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA   Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA   Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA   Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA   Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA   Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA   Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA   Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA   Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA   Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA   Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA   McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA   Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA   Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA   Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA   Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA   Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA   Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA   Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA   Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA   Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA   Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA   Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA   Venter J.C.;
RT   "The genome sequence of Drosophila melanogaster.";
RL   Science 287:2185-2195(2000).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=Berkeley;
RX   PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA   Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA   Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA   Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA   Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA   Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA   Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT   "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT   review.";
RL   Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
CC   -!- DEVELOPMENTAL STAGE: Expressed from the cellular blastoderm stage on,
CC       most during gastrulation and is no longer detected by the end of germ
CC       band extension.
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DR   EMBL; M19140; AAA28928.1; -; mRNA.
DR   EMBL; AE014296; AAF49257.1; -; Genomic_DNA.
DR   PIR; A43741; A43741.
DR   RefSeq; NP_524882.2; NM_080143.4.
DR   AlphaFoldDB; P11455; -.
DR   BioGRID; 70682; 38.
DR   DIP; DIP-17145N; -.
DR   IntAct; P11455; 7.
DR   STRING; 7227.FBpp0074878; -.
DR   PaxDb; P11455; -.
DR   PRIDE; P11455; -.
DR   DNASU; 47208; -.
DR   EnsemblMetazoa; FBtr0075112; FBpp0074878; FBgn0003683.
DR   GeneID; 47208; -.
DR   KEGG; dme:Dmel_CG4216; -.
DR   UCSC; CG4216-RA; d. melanogaster.
DR   CTD; 47208; -.
DR   FlyBase; FBgn0003683; term.
DR   VEuPathDB; VectorBase:FBgn0003683; -.
DR   eggNOG; ENOG502T9CR; Eukaryota.
DR   HOGENOM; CLU_772264_0_0_1; -.
DR   InParanoid; P11455; -.
DR   OMA; LHIHQQL; -.
DR   OrthoDB; 1076108at2759; -.
DR   PhylomeDB; P11455; -.
DR   SignaLink; P11455; -.
DR   BioGRID-ORCS; 47208; 0 hits in 1 CRISPR screen.
DR   GenomeRNAi; 47208; -.
DR   PRO; PR:P11455; -.
DR   Proteomes; UP000000803; Chromosome 3L.
DR   Bgee; FBgn0003683; Expressed in ectoderm and 19 other tissues.
DR   Genevisible; P11455; DM.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR013087; Znf_C2H2_type.
PE   2: Evidence at transcript level;
KW   Developmental protein; DNA-binding; Metal-binding; Reference proteome;
KW   Zinc; Zinc-finger.
FT   CHAIN           1..428
FT                   /note="Protein terminus"
FT                   /id="PRO_0000072487"
FT   ZN_FING         325..346
FT                   /note="C3H1-type"
FT   CONFLICT        144
FT                   /note="A -> V (in Ref. 1; AAA28928)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   428 AA;  49166 MW;  F545653F738AE434 CRC64;
     MFDEPIISSF VFTNEETTQT FHHQWFSQGQ LHECATCYSS IDADEPPSQH WLRGGEASQG
     LHLTKQQQAV MDIIEARQIE TFFFCDESSK DKLEHFMGET CARGIPELLR WMFQNNTVAV
     EFNLACYVNA MDQVLIFQSG SLRADHHYDV DESVGVVYEM LMQRIENYLN CSSEYGMAEC
     SITRLKVQVK RIRVEADGQS ADSSVFALPL QLQEEEGLTA TTGCSTSEAE LASLRSAYLK
     HFRECNGYFP PNMRVNLYGL QQCKTTKELY VVPYHISETL QQLPNKNFLI LNNIMGQFQR
     LHELSTPVNS IERDQTSSPL KDLHCRRCRT QFSRRSKLHI HQKLRCGQDF SVDSMHADIV
     EIYEQCLPIS RSVFQHACYG ITKPKTMMRK GQFVPIECDW RSESSVKVQH GPCVVISNAQ
     HNSPCKFY
 
 
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