TESS_TERAN
ID TESS_TERAN Reviewed; 134 AA.
AC P0DN42;
DT 09-DEC-2015, integrated into UniProtKB/Swiss-Prot.
DT 09-DEC-2015, sequence version 1.
DT 25-MAY-2022, entry version 14.
DE RecName: Full=Terepressin/terephysin {ECO:0000303|PubMed:26025559};
DE AltName: Full=Conopressin/Conophysin-like {ECO:0000303|PubMed:26025559};
DE Contains:
DE RecName: Full=Terepressin {ECO:0000303|PubMed:26025559};
DE AltName: Full=Conopressin-like {ECO:0000303|PubMed:26025559};
DE Contains:
DE RecName: Full=Terephysin {ECO:0000303|PubMed:26025559};
DE AltName: Full=Conophysin-like {ECO:0000303|PubMed:26025559};
DE Flags: Precursor;
OS Terebra anilis (Auger snail) (Cinguloterebra anilis).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Neogastropoda; Conoidea; Terebridae; Terebra.
OX NCBI_TaxID=553697;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom duct;
RX PubMed=26025559; DOI=10.1093/gbe/evv104;
RA Gorson J., Ramrattan G., Verdes A., Wright E.M., Kantor Y.,
RA Rajaram Srinivasan R., Musunuri R., Packer D., Albano G., Qiu W.G.,
RA Holford M.;
RT "Molecular diversity and gene evolution of the venom arsenal of Terebridae
RT predatory marine snails.";
RL Genome Biol. Evol. 7:1761-1778(2015).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:26025559}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC {ECO:0000305|PubMed:26025559}.
CC -!- DOMAIN: The cysteine framework of the terepressin is C-C.
CC {ECO:0000305}.
CC -!- PTM: [Terephysin]: Contains 7 disulfide bonds. {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the vasopressin/oxytocin family. {ECO:0000305}.
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DR AlphaFoldDB; P0DN42; -.
DR SMR; P0DN42; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005185; F:neurohypophyseal hormone activity; IEA:InterPro.
DR Gene3D; 2.60.9.10; -; 1.
DR InterPro; IPR000981; Neurhyp_horm.
DR InterPro; IPR036387; Neurhyp_horm_dom_sf.
DR InterPro; IPR022423; Neurohypophysial_hormone_CS.
DR PANTHER; PTHR11681; PTHR11681; 1.
DR Pfam; PF00184; Hormone_5; 1.
DR PIRSF; PIRSF001815; Nonapeptide_hormone_precursor; 1.
DR PRINTS; PR00831; NEUROPHYSIN.
DR SMART; SM00003; NH; 1.
DR SUPFAM; SSF49606; SSF49606; 1.
PE 2: Evidence at transcript level;
KW Cleavage on pair of basic residues; Disulfide bond; Secreted; Signal.
FT SIGNAL 1..33
FT /evidence="ECO:0000255"
FT PEPTIDE 34..42
FT /note="Terepressin"
FT /id="PRO_0000435046"
FT PROPEP 44..50
FT /evidence="ECO:0000305|PubMed:26025559"
FT /id="PRO_0000435047"
FT CHAIN 51..134
FT /note="Terephysin"
FT /id="PRO_0000435048"
FT DISULFID 34..39
FT /evidence="ECO:0000305"
FT DISULFID 56..100
FT /evidence="ECO:0000250|UniProtKB:P01175"
FT DISULFID 59..73
FT /evidence="ECO:0000250|UniProtKB:P01175"
FT DISULFID 67..90
FT /evidence="ECO:0000250|UniProtKB:P01175"
FT DISULFID 74..80
FT /evidence="ECO:0000250|UniProtKB:P01175"
FT DISULFID 107..121
FT /evidence="ECO:0000250|UniProtKB:P01175"
FT DISULFID 115..133
FT /evidence="ECO:0000250|UniProtKB:P01175"
FT DISULFID 122..127
FT /evidence="ECO:0000250|UniProtKB:P01175"
SQ SEQUENCE 134 AA; 13967 MW; D90E0220944EA10D CRC64;
MKCSVLQMSR LSWTACVLLL PLLLLTLQGG VQGCFIRNCP RGGKRAVDSV QPTRQCMSCG
PEGVGQCVGP SICCGLAIGC LMGTPEAEVC QKENESSAPC AVSGRHCGMD NTGNCVADGI
CCVEDACSFN SLCR
