TET10_ARATH
ID TET10_ARATH Reviewed; 284 AA.
AC F4I214; B9DFW6; F4I213; Q0WS10; Q6NLS7; Q9C8T0;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 61.
DE RecName: Full=Tetraspanin-10;
GN Name=TET10; OrderedLocusNames=At1g63260; ORFNames=F9N12.12;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14993207; DOI=10.1101/gr.1515604;
RA Castelli V., Aury J.-M., Jaillon O., Wincker P., Clepet C., Menard M.,
RA Cruaud C., Quetier F., Scarpelli C., Schaechter V., Temple G., Caboche M.,
RA Weissenbach J., Salanoubat M.;
RT "Whole genome sequence comparisons and 'full-length' cDNA sequences: a
RT combined approach to evaluate and improve Arabidopsis genome annotation.";
RL Genome Res. 14:406-413(2004).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Morosawa T.,
RA Kamiya A., Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K.,
RA Kohara Y., Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K.,
RA Akiyama K., Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J.,
RA Hayashizaki Y., Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the regulation of cell differentiation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=3;
CC Name=1;
CC IsoId=F4I214-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4I214-2; Sequence=VSP_045056, VSP_045057;
CC Name=3;
CC IsoId=F4I214-3; Sequence=VSP_045058;
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG52141.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC022355; AAG52141.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE34077.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34078.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE34079.1; -; Genomic_DNA.
DR EMBL; CP002684; ANM58225.1; -; Genomic_DNA.
DR EMBL; BX816848; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AK316928; BAH19633.1; -; mRNA.
DR EMBL; BT011569; AAS21128.1; -; mRNA.
DR EMBL; BT012253; AAS76740.1; -; mRNA.
DR EMBL; AK228132; BAF00089.1; -; mRNA.
DR PIR; D96658; D96658.
DR RefSeq; NP_001031222.1; NM_001036145.3. [F4I214-3]
DR RefSeq; NP_001320676.1; NM_001334077.1. [F4I214-1]
DR RefSeq; NP_176515.3; NM_105005.5. [F4I214-1]
DR RefSeq; NP_974077.1; NM_202348.3. [F4I214-2]
DR AlphaFoldDB; F4I214; -.
DR STRING; 3702.AT1G63260.1; -.
DR TCDB; 8.A.40.4.2; the tetraspanin (tetraspanin) family.
DR PaxDb; F4I214; -.
DR PRIDE; F4I214; -.
DR ProteomicsDB; 232698; -. [F4I214-1]
DR EnsemblPlants; AT1G63260.1; AT1G63260.1; AT1G63260. [F4I214-1]
DR EnsemblPlants; AT1G63260.2; AT1G63260.2; AT1G63260. [F4I214-2]
DR EnsemblPlants; AT1G63260.3; AT1G63260.3; AT1G63260. [F4I214-3]
DR EnsemblPlants; AT1G63260.6; AT1G63260.6; AT1G63260. [F4I214-1]
DR GeneID; 842632; -.
DR Gramene; AT1G63260.1; AT1G63260.1; AT1G63260. [F4I214-1]
DR Gramene; AT1G63260.2; AT1G63260.2; AT1G63260. [F4I214-2]
DR Gramene; AT1G63260.3; AT1G63260.3; AT1G63260. [F4I214-3]
DR Gramene; AT1G63260.6; AT1G63260.6; AT1G63260. [F4I214-1]
DR KEGG; ath:AT1G63260; -.
DR Araport; AT1G63260; -.
DR TAIR; locus:2038488; AT1G63260.
DR eggNOG; ENOG502QQQM; Eukaryota.
DR InParanoid; F4I214; -.
DR OrthoDB; 963075at2759; -.
DR PRO; PR:F4I214; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; F4I214; baseline and differential.
DR Genevisible; F4I214; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:InterPro.
DR InterPro; IPR044991; TET_plant.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR PANTHER; PTHR32191; PTHR32191; 1.
DR Pfam; PF00335; Tetraspanin; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..284
FT /note="Tetraspanin-10"
FT /id="PRO_0000421050"
FT TOPO_DOM 1..11
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 33..43
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 65..75
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 97..228
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 250..284
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 99
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 128
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 183
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT VAR_SEQ 238..258
FT /note="VLFVVLISSLLSTRFDSEQSF -> SMVYFVGCCARRNAASYRSKA (in
FT isoform 2)"
FT /evidence="ECO:0000303|Ref.5, ECO:0000303|Ref.6"
FT /id="VSP_045056"
FT VAR_SEQ 259..284
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.5, ECO:0000303|Ref.6"
FT /id="VSP_045057"
FT VAR_SEQ 262..284
FT /note="NGLVQISNITFKDCQTTTVPKQF -> NVNGLLCWMLCEKKCC (in
FT isoform 3)"
FT /evidence="ECO:0000303|PubMed:19423640"
FT /id="VSP_045058"
FT CONFLICT 214
FT /note="C -> Y (in Ref. 4; BAH19633)"
FT /evidence="ECO:0000305"
FT CONFLICT 222
FT /note="A -> G (in Ref. 6; BAF00089)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 284 AA; 31919 MW; DA2C4A7F3962F901 CRC64;
MGMGTSTFVI RWVNLLTMLL AVAVIIFGVW MSTHNDGCRR SLTFPVIALG GFIFLISIIG
FLGACKRSVA LLWIYLAVLL IVLIAILVFT VLAFIVTNNG SGHTNPGLRY KEYKLNDYSS
WFLKQLNNTS NWIRLKSCLV KSEQCRKLSK KYKTIKQLKS AELTPIEAGC CRPPSECGYP
AVNASYYDLS FHSISSNKDC KLYKNLRTIK CYNCDSCKAG VAQYMKTEWR LVAIFNVVLF
VVLISSLLST RFDSEQSFGL LNGLVQISNI TFKDCQTTTV PKQF
