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TET11_ARATH
ID   TET11_ARATH             Reviewed;         271 AA.
AC   Q9LPR6; A0ME76; Q8LAM6;
DT   06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Tetraspanin-11;
GN   Name=TET11; OrderedLocusNames=At1g18520; ORFNames=F15H18.1;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the regulation of cell differentiation.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABK28403.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC013354; AAF26004.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE29725.1; -; Genomic_DNA.
DR   EMBL; DQ446262; ABE65632.1; -; mRNA.
DR   EMBL; DQ652844; ABK28403.1; ALT_SEQ; mRNA.
DR   EMBL; AY087722; AAM65259.1; -; mRNA.
DR   RefSeq; NP_564056.1; NM_101710.3.
DR   AlphaFoldDB; Q9LPR6; -.
DR   BioGRID; 23672; 33.
DR   IntAct; Q9LPR6; 28.
DR   STRING; 3702.AT1G18520.1; -.
DR   PaxDb; Q9LPR6; -.
DR   PRIDE; Q9LPR6; -.
DR   ProteomicsDB; 232813; -.
DR   EnsemblPlants; AT1G18520.1; AT1G18520.1; AT1G18520.
DR   GeneID; 838433; -.
DR   Gramene; AT1G18520.1; AT1G18520.1; AT1G18520.
DR   KEGG; ath:AT1G18520; -.
DR   Araport; AT1G18520; -.
DR   TAIR; locus:2014054; AT1G18520.
DR   eggNOG; ENOG502QTNI; Eukaryota.
DR   HOGENOM; CLU_066970_0_0_1; -.
DR   InParanoid; Q9LPR6; -.
DR   OMA; GYKEYRT; -.
DR   OrthoDB; 648926at2759; -.
DR   PhylomeDB; Q9LPR6; -.
DR   PRO; PR:Q9LPR6; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9LPR6; baseline and differential.
DR   Genevisible; Q9LPR6; AT.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR   GO; GO:0009734; P:auxin-activated signaling pathway; IEA:InterPro.
DR   InterPro; IPR044991; TET_plant.
DR   InterPro; IPR018499; Tetraspanin/Peripherin.
DR   PANTHER; PTHR32191; PTHR32191; 1.
DR   Pfam; PF00335; Tetraspanin; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..271
FT                   /note="Tetraspanin-11"
FT                   /id="PRO_0000421051"
FT   TOPO_DOM        1..7
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        29..44
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        45..65
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        66..76
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        98..236
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..257
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        258..271
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        185
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        195
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        8
FT                   /note="M -> V (in Ref. 4; AAM65259)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        199
FT                   /note="V -> VA (in Ref. 4; AAM65259)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        228
FT                   /note="A -> T (in Ref. 4; AAM65259)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   271 AA;  29825 MW;  7C1A3050BF421D55 CRC64;
     MFRVSNFMVG LANTLVMLVG ASAIGYSIYM FVHQGVTDCE SAIRIPLLTT GLILFLVSLL
     GVIGSCFKEN LAMVSYLIIL FGGIVALMIF SIFLFFVTNK GAGRVVSGRG YKEYRTVDFS
     TWLNGFVGGK RWVGIRSCLA EANVCDDLSD GRVSQIADAF YHKNLSPIQS GCCKPPSDCN
     FEFRNATFWI PPSKNETAVA ENGDCGTWSN VQTELCFNCN ACKAGVLANI REKWRNLLVF
     NICLLILLIT VYSCGCCARR NNRTARKSDS V
 
 
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