TET11_ARATH
ID TET11_ARATH Reviewed; 271 AA.
AC Q9LPR6; A0ME76; Q8LAM6;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=Tetraspanin-11;
GN Name=TET11; OrderedLocusNames=At1g18520; ORFNames=F15H18.1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the regulation of cell differentiation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28403.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC013354; AAF26004.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29725.1; -; Genomic_DNA.
DR EMBL; DQ446262; ABE65632.1; -; mRNA.
DR EMBL; DQ652844; ABK28403.1; ALT_SEQ; mRNA.
DR EMBL; AY087722; AAM65259.1; -; mRNA.
DR RefSeq; NP_564056.1; NM_101710.3.
DR AlphaFoldDB; Q9LPR6; -.
DR BioGRID; 23672; 33.
DR IntAct; Q9LPR6; 28.
DR STRING; 3702.AT1G18520.1; -.
DR PaxDb; Q9LPR6; -.
DR PRIDE; Q9LPR6; -.
DR ProteomicsDB; 232813; -.
DR EnsemblPlants; AT1G18520.1; AT1G18520.1; AT1G18520.
DR GeneID; 838433; -.
DR Gramene; AT1G18520.1; AT1G18520.1; AT1G18520.
DR KEGG; ath:AT1G18520; -.
DR Araport; AT1G18520; -.
DR TAIR; locus:2014054; AT1G18520.
DR eggNOG; ENOG502QTNI; Eukaryota.
DR HOGENOM; CLU_066970_0_0_1; -.
DR InParanoid; Q9LPR6; -.
DR OMA; GYKEYRT; -.
DR OrthoDB; 648926at2759; -.
DR PhylomeDB; Q9LPR6; -.
DR PRO; PR:Q9LPR6; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9LPR6; baseline and differential.
DR Genevisible; Q9LPR6; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:InterPro.
DR InterPro; IPR044991; TET_plant.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR PANTHER; PTHR32191; PTHR32191; 1.
DR Pfam; PF00335; Tetraspanin; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..271
FT /note="Tetraspanin-11"
FT /id="PRO_0000421051"
FT TOPO_DOM 1..7
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..44
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..76
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 98..236
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 237..257
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 258..271
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 185
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 195
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 8
FT /note="M -> V (in Ref. 4; AAM65259)"
FT /evidence="ECO:0000305"
FT CONFLICT 199
FT /note="V -> VA (in Ref. 4; AAM65259)"
FT /evidence="ECO:0000305"
FT CONFLICT 228
FT /note="A -> T (in Ref. 4; AAM65259)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 271 AA; 29825 MW; 7C1A3050BF421D55 CRC64;
MFRVSNFMVG LANTLVMLVG ASAIGYSIYM FVHQGVTDCE SAIRIPLLTT GLILFLVSLL
GVIGSCFKEN LAMVSYLIIL FGGIVALMIF SIFLFFVTNK GAGRVVSGRG YKEYRTVDFS
TWLNGFVGGK RWVGIRSCLA EANVCDDLSD GRVSQIADAF YHKNLSPIQS GCCKPPSDCN
FEFRNATFWI PPSKNETAVA ENGDCGTWSN VQTELCFNCN ACKAGVLANI REKWRNLLVF
NICLLILLIT VYSCGCCARR NNRTARKSDS V