TET14_ARATH
ID TET14_ARATH Reviewed; 260 AA.
AC Q58G33; Q8GUT9; Q9ZPS8;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 26-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=Tetraspanin-14;
GN Name=TET14; OrderedLocusNames=At2g01960; ORFNames=F14H20.3;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=12481096; DOI=10.1104/pp.010207;
RA Xiao Y.-L., Malik M., Whitelaw C.A., Town C.D.;
RT "Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2
RT of Arabidopsis.";
RL Plant Physiol. 130:2118-2128(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the regulation of cell differentiation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAD20089.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC006532; AAD20089.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC05527.1; -; Genomic_DNA.
DR EMBL; AY168991; AAO11662.1; -; mRNA.
DR EMBL; AY954776; AAX55102.1; -; mRNA.
DR PIR; C84431; C84431.
DR RefSeq; NP_178305.2; NM_126257.3.
DR AlphaFoldDB; Q58G33; -.
DR STRING; 3702.AT2G01960.1; -.
DR TCDB; 8.A.40.6.1; the tetraspanin (tetraspanin) family.
DR PaxDb; Q58G33; -.
DR PRIDE; Q58G33; -.
DR ProteomicsDB; 226601; -.
DR EnsemblPlants; AT2G01960.1; AT2G01960.1; AT2G01960.
DR GeneID; 814727; -.
DR Gramene; AT2G01960.1; AT2G01960.1; AT2G01960.
DR KEGG; ath:AT2G01960; -.
DR Araport; AT2G01960; -.
DR TAIR; locus:2041155; AT2G01960.
DR HOGENOM; CLU_1079044_0_0_1; -.
DR OMA; MWRHELS; -.
DR OrthoDB; 960967at2759; -.
DR PhylomeDB; Q58G33; -.
DR PRO; PR:Q58G33; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q58G33; baseline and differential.
DR Genevisible; Q58G33; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:InterPro.
DR InterPro; IPR044991; TET_plant.
DR PANTHER; PTHR32191; PTHR32191; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..260
FT /note="Tetraspanin-14"
FT /id="PRO_0000421054"
FT TOPO_DOM 1..10
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 11..31
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 32..54
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..80
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 102..260
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT CARBOHYD 182
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 260 AA; 30549 MW; 812A0814BF1C27AD CRC64;
MKSQSHKPWN LVAGIFFPII TFFLSAPLVG HALYLFCMRN DHVYYRDFQS TLPRVQTLVS
VSLLALFLLS NIGMFLRPRR LSYFLVIVFF IGFAYSGVYK MESRRFSPTP MCFKGEYNNG
QGERKTEQYQ VVKIEQSQGR LQRVHLRFVN SYALPPYDRR LLPSVKTGCC NRPGNCKLET
VNATLWVTRN REGPPLETAM IYDRYGGNAD IKDYYDMWRH ELSVLYYDCM TCQVRIIKSP
RLRKWWQFGV FLSSLTSLFR
