TET15_ARATH
ID TET15_ARATH Reviewed; 317 AA.
AC Q1PDI1; A0MFQ2; Q8LCX7; Q9FJN3;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Tetraspanin-15;
GN Name=TET15; OrderedLocusNames=At5g57810; ORFNames=MTI20.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the regulation of cell differentiation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=ABK28764.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
CC Sequence=BAB08851.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AB013396; BAB08851.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002688; AED96954.1; -; Genomic_DNA.
DR EMBL; DQ447087; ABE66257.1; -; mRNA.
DR EMBL; DQ653378; ABK28764.1; ALT_SEQ; mRNA.
DR EMBL; AY086342; AAM64410.1; -; mRNA.
DR RefSeq; NP_568866.1; NM_125165.3.
DR AlphaFoldDB; Q1PDI1; -.
DR SMR; Q1PDI1; -.
DR BioGRID; 21134; 7.
DR IntAct; Q1PDI1; 6.
DR STRING; 3702.AT5G57810.1; -.
DR TCDB; 8.A.40.6.2; the tetraspanin (tetraspanin) family.
DR PaxDb; Q1PDI1; -.
DR PRIDE; Q1PDI1; -.
DR ProteomicsDB; 226602; -.
DR EnsemblPlants; AT5G57810.1; AT5G57810.1; AT5G57810.
DR GeneID; 835890; -.
DR Gramene; AT5G57810.1; AT5G57810.1; AT5G57810.
DR KEGG; ath:AT5G57810; -.
DR Araport; AT5G57810; -.
DR TAIR; locus:2174383; AT5G57810.
DR eggNOG; ENOG502RVM0; Eukaryota.
DR HOGENOM; CLU_066970_0_0_1; -.
DR InParanoid; Q1PDI1; -.
DR OMA; MRDYDCE; -.
DR OrthoDB; 960967at2759; -.
DR PhylomeDB; Q1PDI1; -.
DR PRO; PR:Q1PDI1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q1PDI1; baseline and differential.
DR Genevisible; Q1PDI1; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:InterPro.
DR InterPro; IPR044991; TET_plant.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR PANTHER; PTHR32191; PTHR32191; 1.
DR Pfam; PF00335; Tetraspanin; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..317
FT /note="Tetraspanin-15"
FT /id="PRO_0000421055"
FT TOPO_DOM 1..60
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 82..96
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 118..126
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 127..147
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 148..287
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 309..317
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CARBOHYD 224
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 268
FT /note="Y -> N (in Ref. 4; AAM64410)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 317 AA; 35880 MW; 1E9D7974CC00178A CRC64;
MADNAQVVPV EEPAATATAT ATATATTEPE AKSSDQMESQ SDNKPPMGTL MALVNILAAG
VLPIFTFVLS LTLLGYAVWL LYMRSYDCED ILGLPRVQTL ASVGLLAVFV VSNAALFLRR
KFPMPALVVM VVVLLLMLFI GLAYAGVNEM QSRRFPATRM WFKLKIMDDH VTWNNIKSCV
YDKGACNDLI YGSPNEKPYN RRKMPPIKNG CCMPPETCNM DAINATFWYR RKDEGPPSSM
NLMYGDEMMV GRISDCQLWR NDWSILCYDC RSCKFGFIRS VRRKWWQLGI FLIVISILLL
MSHLLIFLAT FWERFKG
