TET16_ARATH
ID TET16_ARATH Reviewed; 248 AA.
AC Q5BQ04; F4IC96; Q5Q0G5; Q9LPR5;
DT 06-FEB-2013, integrated into UniProtKB/Swiss-Prot.
DT 12-APR-2005, sequence version 1.
DT 03-AUG-2022, entry version 75.
DE RecName: Full=Tetraspanin-16;
GN Name=TET16; OrderedLocusNames=At1g18510; ORFNames=F15H18.2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Xiao Y.-L., Underwood B.A., Moskal W.A. Jr., Torian U., Redman J.C.,
RA Wu H.C., Utterback T., Town C.D.;
RT "Reconstruction of cDNA sequences for hypothetical genes in Arabidopsis
RT thaliana from 5' and 3' RACE products.";
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in the regulation of cell differentiation.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF26003.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC013354; AAF26003.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE29724.2; -; Genomic_DNA.
DR EMBL; AY924674; AAX23749.1; -; mRNA.
DR EMBL; AY800586; AAV68822.1; -; mRNA.
DR PIR; F86318; F86318.
DR RefSeq; NP_173286.2; NM_101709.2.
DR AlphaFoldDB; Q5BQ04; -.
DR STRING; 3702.AT1G18510.1; -.
DR TCDB; 8.A.40.4.3; the tetraspanin (tetraspanin) family.
DR PaxDb; Q5BQ04; -.
DR PRIDE; Q5BQ04; -.
DR EnsemblPlants; AT1G18510.1; AT1G18510.1; AT1G18510.
DR GeneID; 838432; -.
DR Gramene; AT1G18510.1; AT1G18510.1; AT1G18510.
DR KEGG; ath:AT1G18510; -.
DR Araport; AT1G18510; -.
DR TAIR; locus:2014064; AT1G18510.
DR HOGENOM; CLU_1121427_0_0_1; -.
DR InParanoid; Q5BQ04; -.
DR OMA; WRYCCAQ; -.
DR OrthoDB; 1012680at2759; -.
DR PhylomeDB; Q5BQ04; -.
DR PRO; PR:Q5BQ04; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q5BQ04; baseline and differential.
DR Genevisible; Q5BQ04; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0009506; C:plasmodesma; IBA:GO_Central.
DR GO; GO:0009734; P:auxin-activated signaling pathway; IEA:InterPro.
DR InterPro; IPR044991; TET_plant.
DR PANTHER; PTHR32191; PTHR32191; 1.
PE 2: Evidence at transcript level;
KW Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..248
FT /note="Tetraspanin-16"
FT /id="PRO_0000421056"
FT TOPO_DOM 1..7
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 29..44
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 45..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 66..69
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 91..208
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 209..229
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 230..248
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT CARBOHYD 96
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 141
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CONFLICT 41
FT /note="T -> A (in Ref. 3; AAV68822)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 248 AA; 28224 MW; D8A75281EA9BD9FD CRC64;
MSEIRTGFLT MATIILICIG LTMTGTGLYY RKTVSKCIRE TDGSFVVIGL LLLVIPQFAL
YAICCHSKRM FTIYIYAMIF VSIVLGGYSL KCFIYNTTFG IAKNPAEEKR TAKQLVGRLV
PESKLAKVTE CIIHNHDCNF NASQNSNVWR YCCAQPRGCG VTTMFGQPGE WSWKHQHVEN
HVPEECSYEY CLSCRGCQMS ILKAIVHQWK YLSMFSYPAL FLVCLSLAIS RSIMDTFDEP
DDYRGYYS
