ID   TEV3_BPR03              Reviewed;         269 AA.
AC   Q38419;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 53.
DE   RecName: Full=Intron-associated endonuclease 3;
DE            EC=3.1.-.-;
DE   AltName: Full=I-TevIII;
GN   Name=ITEVIIIR;
OS   Enterobacteria phage RB3 (Bacteriophage RB3).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=31533;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2044951; DOI=10.1101/gad.5.6.1032;
RA   Eddy S.R., Gold L.;
RT   "The phage T4 nrdB intron: a deletion mutant of a version found in the
RT   wild.";
RL   Genes Dev. 5:1032-1041(1991).
CC   -!- FUNCTION: This endonuclease is specific to the nrdB gene splice
CC       junction and is involved in intron homing.
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DR   EMBL; X59078; CAA41802.1; -; Genomic_DNA.
DR   RefSeq; YP_009098611.1; NC_025419.1.
DR   REBASE; 2626; I-TevIII.
DR   GeneID; 22113975; -.
DR   KEGG; vg:22113975; -.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006314; P:intron homing; IEA:UniProtKB-KW.
DR   CDD; cd00085; HNHc; 1.
DR   InterPro; IPR031316; FlgM_C.
DR   InterPro; IPR044925; His-Me_finger_sf.
DR   InterPro; IPR003615; HNH_nuc.
DR   Pfam; PF04316; FlgM; 1.
DR   Pfam; PF13392; HNH_3; 1.
DR   SUPFAM; SSF54060; SSF54060; 1.
PE   4: Predicted;
KW   Endonuclease; Hydrolase; Intron homing; Nuclease.
FT   CHAIN           1..269
FT                   /note="Intron-associated endonuclease 3"
FT                   /id="PRO_0000192794"
SQ   SEQUENCE   269 AA;  30814 MW;  80F8B5A7AC580A86 CRC64;
     MNYRKIWIDA NGPIPKDSDG RTDEIHHKDG NRENNDLDNL MCLSIQEHYD IHLAQKDYQA
     CHAIKLRMKY SPEEISELAS KAAKSREIQI FNIPEVRAKN IASIKSKIEN GTFHLLDGEI
     QRKSNLNRVA LGIHNFQQAE HIAKVKERNI AAIKEGTHVF CGGKMQSETQ SKRVNDGSHH
     FLSEDHKKRT SAKTLEMVKN GTHPAQKEIT CDFCGHIGKG PGFYLKHNDR CKLNPNRIQL
     NCPYCDKKDL SPSTYKRWHG DNCKARFND