ID   TEX10_CHICK             Reviewed;         927 AA.
AC   Q5ZM41;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Testis-expressed protein 10 homolog;
GN   Name=TEX10; ORFNames=RCJMB04_3d16;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: Component of the PELP1 complex involved in the nucleolar
CC       steps of 28S rRNA maturation and the subsequent nucleoplasmic transit
CC       of the pre-60S ribosomal subunit. {ECO:0000250|UniProtKB:Q9NXF1}.
CC   -!- SUBUNIT: Component of some MLL1/MLL complex. Component of the PELP1
CC       complex, composed of at least PELP1, TEX10 and WDR18. The complex
CC       interacts with pre-60S ribosome particles.
CC       {ECO:0000250|UniProtKB:Q9NXF1}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleoplasm
CC       {ECO:0000250|UniProtKB:Q3URQ0}. Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q9NXF1}.
CC   -!- SIMILARITY: Belongs to the IPI1/TEX10 family. {ECO:0000305}.
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DR   EMBL; AJ719543; CAG31202.1; -; mRNA.
DR   RefSeq; NP_001026179.1; NM_001031008.2.
DR   AlphaFoldDB; Q5ZM41; -.
DR   STRING; 9031.ENSGALP00000021875; -.
DR   PaxDb; Q5ZM41; -.
DR   GeneID; 420993; -.
DR   KEGG; gga:420993; -.
DR   CTD; 54881; -.
DR   VEuPathDB; HostDB:geneid_420993; -.
DR   eggNOG; KOG2149; Eukaryota.
DR   InParanoid; Q5ZM41; -.
DR   OrthoDB; 1285836at2759; -.
DR   PhylomeDB; Q5ZM41; -.
DR   PRO; PR:Q5ZM41; -.
DR   Proteomes; UP000000539; Unplaced.
DR   GO; GO:0071339; C:MLL1 complex; ISS:UniProtKB.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR024679; Ipi1_N.
DR   InterPro; IPR037947; TEX10/Ipi1.
DR   PANTHER; PTHR16056:SF2; PTHR16056:SF2; 1.
DR   Pfam; PF12333; Ipi1_N; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..927
FT                   /note="Testis-expressed protein 10 homolog"
FT                   /id="PRO_0000072490"
FT   REPEAT          99..137
FT                   /note="HEAT"
SQ   SEQUENCE   927 AA;  105390 MW;  2B94226526B78D8E CRC64;
     MTKKRKHQED FQKVKLKVGK KKPKLENATD TTFKTKAIQI PEQLKEDGML TTQNRKLNIK
     DLLSQMHHYS PGVKQNALLG LKDLLSQYPF LIDAHLSNII SEVAAVFTDK DSGVRGAAVH
     LLQFLASKIR AEQIAPFFPL VSAHLSSAMT HISEGIQEDS LKVLDILLEA YPALLTDRSS
     ILLKNFVELI SHQQLSKRLK SKEKLSWMLS VNPNRRVTSQ QWRLNVLIRL KKFLQAVVDG
     SNETEDEGLQ EQKDSPHSVR NPIFISWKVH ANNQQHIHLY ENGGLRPKMS SSFRLRSLAS
     VMDSAEKGLS SAENLKGFIE IIIPLLIECW IEASPAQSAP ILGNLLESDC QQLMQQVLSI
     IHLLWKLTKR HDETYKMEVW LRMNYLVDFK HHFMRNFPYS LQETVKHKKK DSCKGNKYCT
     TSSNNVDHLL LNLTLCDIMV SLASASTLQA DSGWLDMIRN FVTDTLQDGS RLNSKQVNRL
     LGVTWRLMQI QQNKVATEPL IKAVYTLYQQ RNLLFPVRTL LLKFFSRVYQ KEDSKTQRIR
     SRSKVLSRWL AGLPQQLALL GLRNPELSNQ LIDIIHSAAS RSNKELLQSL QATAVQIYDP
     LGGTLVLLPA EAQRRLVQLV YFLPCLPTSL LACLSRCCIM GRMSSELAAT LIGILRMRSS
     FAGWKCQVQD NAVNDVDYFS FLFSTLIGFS REELTSLQGI RGKPHISQTQ LSPVRLYLTD
     LDQFLHHWAV TEVICHSLST IPSQSQCFDI LQTGICKYLV GLVVIPDSTA GSVLCAINKL
     LDQACILSEN LHKFLASCCY SLLYFLLTLD KEDAEHVQKR DMLWGSCISA LALLPRLLRL
     MLQSLQVSRI CREELPVVAQ LLRLLMQHGQ LRSHMMTNEF LVQQIIKDIM TLKSGEVQEQ
     WLTDLHYCFN IYLASHPQGP SPMNAVY