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TEX24_MOUSE
ID   TEX24_MOUSE             Reviewed;         351 AA.
AC   Q5DP50;
DT   17-FEB-2016, integrated into UniProtKB/Swiss-Prot.
DT   29-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Protein Tex24 {ECO:0000305};
DE   AltName: Full=Testis-expressed protein 24 {ECO:0000312|MGI:MGI:1921539};
DE   AltName: Full=Testis-specific factor 1 {ECO:0000303|PubMed:16343427};
GN   Name=Tex24 {ECO:0000312|MGI:MGI:1921539};
GN   Synonyms=TESF-1 {ECO:0000303|PubMed:16343427};
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1] {ECO:0000312|EMBL:AAT36321.1}
RP   NUCLEOTIDE SEQUENCE [MRNA], PUTATIVE FUNCTION, SUBCELLULAR LOCATION, AND
RP   TISSUE SPECIFICITY.
RC   STRAIN=BALB/cJ {ECO:0000312|EMBL:AAT36321.1};
RC   TISSUE=Testis {ECO:0000312|EMBL:AAT36321.1};
RX   PubMed=16343427; DOI=10.1016/j.bbrc.2005.11.152;
RA   Fan J., Graham M., Akabane H., Richardson L.L., Zhu G.Z.;
RT   "Identification of a novel male germ cell-specific gene TESF-1 in mice.";
RL   Biochem. Biophys. Res. Commun. 340:8-12(2006).
RN   [2] {ECO:0000312|Proteomes:UP000000589}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [3] {ECO:0000312|EMBL:AAI39072.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: Nuclear factor which might have a role in spermatogenesis.
CC       {ECO:0000305|PubMed:16343427}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16343427}.
CC   -!- TISSUE SPECIFICITY: Specific to testis, where it is expressed in
CC       spermatogonia. {ECO:0000269|PubMed:16343427}.
CC   -!- DEVELOPMENTAL STAGE: Detected in testis from postnatal day 20 onwards.
CC       {ECO:0000269|PubMed:16343427}.
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DR   EMBL; AY552600; AAT36321.1; -; mRNA.
DR   EMBL; AC102544; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC139071; AAI39072.1; -; mRNA.
DR   EMBL; BC139072; AAI39073.1; -; mRNA.
DR   CCDS; CCDS22215.1; -.
DR   RefSeq; NP_001013627.1; NM_001013609.2.
DR   RefSeq; XP_006509234.1; XM_006509171.2.
DR   AlphaFoldDB; Q5DP50; -.
DR   STRING; 10090.ENSMUSP00000093021; -.
DR   iPTMnet; Q5DP50; -.
DR   PhosphoSitePlus; Q5DP50; -.
DR   PaxDb; Q5DP50; -.
DR   PRIDE; Q5DP50; -.
DR   ProteomicsDB; 259006; -.
DR   DNASU; 541463; -.
DR   Ensembl; ENSMUST00000095375; ENSMUSP00000093021; ENSMUSG00000071138.
DR   GeneID; 541463; -.
DR   KEGG; mmu:541463; -.
DR   UCSC; uc009lir.1; mouse.
DR   CTD; 541463; -.
DR   MGI; MGI:1921539; Tex24.
DR   VEuPathDB; HostDB:ENSMUSG00000071138; -.
DR   GeneTree; ENSGT00520000061098; -.
DR   HOGENOM; CLU_789783_0_0_1; -.
DR   InParanoid; Q5DP50; -.
DR   OMA; ERNIARP; -.
DR   OrthoDB; 1186441at2759; -.
DR   BioGRID-ORCS; 541463; 3 hits in 71 CRISPR screens.
DR   PRO; PR:Q5DP50; -.
DR   Proteomes; UP000000589; Chromosome 8.
DR   RNAct; Q5DP50; protein.
DR   Bgee; ENSMUSG00000071138; Expressed in seminiferous tubule of testis and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; IDA:MGI.
DR   GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IBA:GO_Central.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   InterPro; IPR043198; Cyclin/Ssn8.
DR   PANTHER; PTHR10026; PTHR10026; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..351
FT                   /note="Protein Tex24"
FT                   /id="PRO_0000435468"
FT   REGION          69..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          117..144
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          275..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   351 AA;  38993 MW;  57BAF253A68FA048 CRC64;
     MGSQSLNSTF LKVRRLSLIS SNERLLGQTS GLATGSRLVT QEVDDLRVIP GSRPDLDDHQ
     PQCSLAELPS TAHGKRKPGH LPRLRSSAVK GHAPDPNPSL SIVSKRIFKG ESVIKGPEDR
     QTFVGPSGLP KISPKATAGE AQGKKRTMEL LNKARKQEEK VSNLLDIRQL PKQEVFINNT
     HPCKKHLKQQ PMSLEEWRRG HLGGDNTGLI SQEPFRCCKR LGKKAQCQLL EVTSLEAEAS
     LEVLKRRRRM QAMEMSKKPQ DRGLGQEKAV FLSREKVKPS SHDMHLSTAE RSFKPKSMPK
     AEDWDLSVQG TPVVLTVRDH SNVSQAQKHL GCAEIFHSRD GRCTLLKRGG A
 
 
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