TEX29_HUMAN
ID TEX29_HUMAN Reviewed; 151 AA.
AC Q8N6K0;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 124.
DE RecName: Full=Testis-expressed protein 29;
GN Name=TEX29; Synonyms=C13orf16;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15057823; DOI=10.1038/nature02379;
RA Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E., Griffiths-Jones S.,
RA Jones M.C., Keenan S.J., Oliver K., Scott C.E., Ainscough R., Almeida J.P.,
RA Ambrose K.D., Andrews D.T., Ashwell R.I.S., Babbage A.K., Bagguley C.L.,
RA Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P.,
RA Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C.,
RA Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P.,
RA Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L.,
RA Frankish A.G., Frankland J., French L., Garner P., Garnett J.,
RA Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M.,
RA Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D.,
RA Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D.,
RA Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S.,
RA Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J.,
RA Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S.,
RA Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R.,
RA Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W.,
RA Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P.,
RA Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L.,
RA Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R.,
RA Rogers J., Ross M.T.;
RT "The DNA sequence and analysis of human chromosome 13.";
RL Nature 428:522-528(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q8N6K0; P05090: APOD; NbExp=3; IntAct=EBI-19027521, EBI-715495;
CC Q8N6K0; Q6UVW9: CLEC2A; NbExp=3; IntAct=EBI-19027521, EBI-15839595;
CC Q8N6K0; Q9BXN2-6: CLEC7A; NbExp=3; IntAct=EBI-19027521, EBI-11989440;
CC Q8N6K0; A0PK11: CLRN2; NbExp=3; IntAct=EBI-19027521, EBI-12813623;
CC Q8N6K0; Q96FZ5: CMTM7; NbExp=3; IntAct=EBI-19027521, EBI-2807956;
CC Q8N6K0; Q96Q80: DERL3; NbExp=3; IntAct=EBI-19027521, EBI-12831318;
CC Q8N6K0; Q92520: FAM3C; NbExp=3; IntAct=EBI-19027521, EBI-2876774;
CC Q8N6K0; P29033: GJB2; NbExp=3; IntAct=EBI-19027521, EBI-3905204;
CC Q8N6K0; Q86YW7: GPHB5; NbExp=3; IntAct=EBI-19027521, EBI-11659720;
CC Q8N6K0; P21145: MAL; NbExp=3; IntAct=EBI-19027521, EBI-3932027;
CC Q8N6K0; Q8N912: NRAC; NbExp=3; IntAct=EBI-19027521, EBI-12051377;
CC Q8N6K0; Q02094: RHAG; NbExp=3; IntAct=EBI-19027521, EBI-14772355;
CC Q8N6K0; Q96GQ5: RUSF1; NbExp=3; IntAct=EBI-19027521, EBI-8636004;
CC Q8N6K0; Q8TB61: SLC35B2; NbExp=3; IntAct=EBI-19027521, EBI-1054782;
CC Q8N6K0; Q9NRQ5: SMCO4; NbExp=3; IntAct=EBI-19027521, EBI-8640191;
CC Q8N6K0; P55061: TMBIM6; NbExp=3; IntAct=EBI-19027521, EBI-1045825;
CC Q8N6K0; P17152: TMEM11; NbExp=3; IntAct=EBI-19027521, EBI-723946;
CC Q8N6K0; Q9NV12: TMEM140; NbExp=3; IntAct=EBI-19027521, EBI-2844246;
CC Q8N6K0; Q9BVK8: TMEM147; NbExp=3; IntAct=EBI-19027521, EBI-348587;
CC Q8N6K0; Q96HH6: TMEM19; NbExp=3; IntAct=EBI-19027521, EBI-741829;
CC Q8N6K0; Q8WZ59: TMEM190; NbExp=3; IntAct=EBI-19027521, EBI-10278423;
CC Q8N6K0; Q8N661: TMEM86B; NbExp=3; IntAct=EBI-19027521, EBI-2548832;
CC Q8N6K0; O95159: ZFPL1; NbExp=3; IntAct=EBI-19027521, EBI-718439;
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AL160395; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC029889; AAH29889.1; -; mRNA.
DR CCDS; CCDS9522.1; -.
DR RefSeq; NP_001290062.1; NM_001303133.1.
DR RefSeq; NP_689537.1; NM_152324.2.
DR AlphaFoldDB; Q8N6K0; -.
DR BioGRID; 125748; 48.
DR IntAct; Q8N6K0; 35.
DR STRING; 9606.ENSP00000283547; -.
DR BioMuta; TEX29; -.
DR DMDM; 74751059; -.
DR MassIVE; Q8N6K0; -.
DR PaxDb; Q8N6K0; -.
DR PeptideAtlas; Q8N6K0; -.
DR PRIDE; Q8N6K0; -.
DR ProteomicsDB; 72183; -.
DR Antibodypedia; 67738; 1 antibodies from 1 providers.
DR DNASU; 121793; -.
DR Ensembl; ENST00000283547.2; ENSP00000283547.1; ENSG00000153495.11.
DR GeneID; 121793; -.
DR KEGG; hsa:121793; -.
DR MANE-Select; ENST00000283547.2; ENSP00000283547.1; NM_152324.3; NP_689537.1.
DR UCSC; uc001vsa.3; human.
DR CTD; 121793; -.
DR DisGeNET; 121793; -.
DR GeneCards; TEX29; -.
DR HGNC; HGNC:20370; TEX29.
DR HPA; ENSG00000153495; Tissue enhanced (brain, testis).
DR neXtProt; NX_Q8N6K0; -.
DR OpenTargets; ENSG00000153495; -.
DR PharmGKB; PA134935852; -.
DR VEuPathDB; HostDB:ENSG00000153495; -.
DR eggNOG; ENOG502RWPU; Eukaryota.
DR GeneTree; ENSGT00510000049560; -.
DR HOGENOM; CLU_147471_0_0_1; -.
DR InParanoid; Q8N6K0; -.
DR OMA; EPEFKKS; -.
DR OrthoDB; 1499909at2759; -.
DR PhylomeDB; Q8N6K0; -.
DR TreeFam; TF337066; -.
DR PathwayCommons; Q8N6K0; -.
DR SignaLink; Q8N6K0; -.
DR BioGRID-ORCS; 121793; 11 hits in 1071 CRISPR screens.
DR ChiTaRS; TEX29; human.
DR GenomeRNAi; 121793; -.
DR Pharos; Q8N6K0; Tdark.
DR PRO; PR:Q8N6K0; -.
DR Proteomes; UP000005640; Chromosome 13.
DR RNAct; Q8N6K0; protein.
DR Bgee; ENSG00000153495; Expressed in left testis and 101 other tissues.
DR ExpressionAtlas; Q8N6K0; baseline and differential.
DR Genevisible; Q8N6K0; HS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR031685; TEX29.
DR Pfam; PF15839; TEX29; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..151
FT /note="Testis-expressed protein 29"
FT /id="PRO_0000263699"
FT TOPO_DOM 1..56
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 57..77
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 78..151
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT REGION 100..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 151 AA; 16649 MW; 42B72FBDFF15C83C CRC64;
MEYVLEVKNS PRHLLKQFTV CDVPLYDICD YNVSRDRCQE LGCCFYEGVC YKKAVPIYIH
VFSALIVIIA GAFVITIIYR VIQESRKEKA IPVDVALPQK SSEKAELASS SSKLGLKPAS
PGPPSAGPSM KSDEDKDDVT GTITEAEETE D
