TEX30_MOUSE
ID TEX30_MOUSE Reviewed; 225 AA.
AC Q3TUU5; Q4KKZ6; Q9D9T9;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 101.
DE RecName: Full=Testis-expressed protein 30;
GN Name=Tex30;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Embryonic stem cell, and Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain, and Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI16882.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAI19033.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AK006487; BAB24612.1; -; mRNA.
DR EMBL; AK160565; BAE35876.1; -; mRNA.
DR EMBL; BC099557; AAH99557.2; -; mRNA.
DR EMBL; BC116881; AAI16882.1; ALT_INIT; mRNA.
DR EMBL; BC119032; AAI19033.1; ALT_INIT; mRNA.
DR CCDS; CCDS48249.1; -.
DR RefSeq; NP_083644.1; NM_029368.1.
DR RefSeq; XP_006496377.1; XM_006496314.3.
DR RefSeq; XP_006496378.1; XM_006496315.3.
DR RefSeq; XP_011236917.1; XM_011238615.2.
DR RefSeq; XP_011236918.1; XM_011238616.2.
DR AlphaFoldDB; Q3TUU5; -.
DR SMR; Q3TUU5; -.
DR STRING; 10090.ENSMUSP00000027215; -.
DR ESTHER; mouse-Tex30; NLS3-Tex30.
DR MEROPS; S09.027; -.
DR iPTMnet; Q3TUU5; -.
DR PhosphoSitePlus; Q3TUU5; -.
DR EPD; Q3TUU5; -.
DR MaxQB; Q3TUU5; -.
DR PaxDb; Q3TUU5; -.
DR PeptideAtlas; Q3TUU5; -.
DR PRIDE; Q3TUU5; -.
DR ProteomicsDB; 259007; -.
DR Antibodypedia; 25333; 22 antibodies from 9 providers.
DR Ensembl; ENSMUST00000027215; ENSMUSP00000027215; ENSMUSG00000026049.
DR Ensembl; ENSMUST00000128190; ENSMUSP00000117565; ENSMUSG00000026049.
DR Ensembl; ENSMUST00000133677; ENSMUSP00000115068; ENSMUSG00000026049.
DR Ensembl; ENSMUST00000147571; ENSMUSP00000114624; ENSMUSG00000026049.
DR Ensembl; ENSMUST00000150911; ENSMUSP00000120928; ENSMUSG00000026049.
DR Ensembl; ENSMUST00000152239; ENSMUSP00000114991; ENSMUSG00000026049.
DR Ensembl; ENSMUST00000156392; ENSMUSP00000121035; ENSMUSG00000026049.
DR GeneID; 75623; -.
DR KEGG; mmu:75623; -.
DR UCSC; uc007avx.2; mouse.
DR CTD; 93081; -.
DR MGI; MGI:1922873; Tex30.
DR VEuPathDB; HostDB:ENSMUSG00000026049; -.
DR eggNOG; KOG3253; Eukaryota.
DR GeneTree; ENSGT00940000162655; -.
DR HOGENOM; CLU_072792_2_0_1; -.
DR InParanoid; Q3TUU5; -.
DR OMA; HWIDKAN; -.
DR OrthoDB; 1183730at2759; -.
DR PhylomeDB; Q3TUU5; -.
DR TreeFam; TF332335; -.
DR BioGRID-ORCS; 75623; 3 hits in 69 CRISPR screens.
DR ChiTaRS; Tex30; mouse.
DR PRO; PR:Q3TUU5; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q3TUU5; protein.
DR Bgee; ENSMUSG00000026049; Expressed in seminiferous tubule of testis and 231 other tissues.
DR ExpressionAtlas; Q3TUU5; baseline and differential.
DR Genevisible; Q3TUU5; MM.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; -; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002925; Dienelactn_hydro.
DR InterPro; IPR026555; NSL3/Tex30.
DR PANTHER; PTHR13136; PTHR13136; 1.
DR Pfam; PF01738; DLH; 1.
DR SUPFAM; SSF53474; SSF53474; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..225
FT /note="Testis-expressed protein 30"
FT /id="PRO_0000274313"
FT CONFLICT 57
FT /note="H -> N (in Ref. 1; BAB24612)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 225 AA; 25263 MW; 3F0BD729CB9135AE CRC64;
MSHTEVKLKI PFGNKLLDAV CLVPNKNIAY GIILTHGASG DMNLPHLMSL ASHLASHGFF
CLRFTCKGLN IVHRIKAYKA VLNYLKTSGE YKLAGVFLGG RSMGSRAAAS VMCHTEPDDA
DDFVRGLICI SYPLHHPKQQ HKLRDEDLFR IKDPVLFVSG SADEMCEKNL LEKVAQKMQA
PSKIHWIEKA NHSMAVKGRS TNDVFKEINT QILFWIQEIT EMDKK