TEX43_HUMAN
ID TEX43_HUMAN Reviewed; 134 AA.
AC Q6ZNM6;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=Testis-expressed protein 43;
GN Name=TEX43; Synonyms=C5orf48;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q6ZNM6; Q53EP0-3: FNDC3B; NbExp=3; IntAct=EBI-18115728, EBI-10242151;
CC Q6ZNM6; Q9Y4Y9: LSM5; NbExp=3; IntAct=EBI-18115728, EBI-373007;
CC Q6ZNM6; Q9UPY8: MAPRE3; NbExp=3; IntAct=EBI-18115728, EBI-726739;
CC Q6ZNM6; Q16656-4: NRF1; NbExp=3; IntAct=EBI-18115728, EBI-11742836;
CC Q6ZNM6; O15160: POLR1C; NbExp=3; IntAct=EBI-18115728, EBI-1055079;
CC Q6ZNM6; P21673: SAT1; NbExp=3; IntAct=EBI-18115728, EBI-711613;
CC Q6ZNM6; P36508: ZNF76; NbExp=3; IntAct=EBI-18115728, EBI-7254550;
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DR EMBL; AK131015; BAC85477.1; -; mRNA.
DR EMBL; AC099513; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC130495; AAI30496.1; -; mRNA.
DR EMBL; BC130497; AAI30498.1; -; mRNA.
DR CCDS; CCDS4139.1; -.
DR RefSeq; NP_997291.1; NM_207408.1.
DR AlphaFoldDB; Q6ZNM6; -.
DR BioGRID; 133087; 9.
DR IntAct; Q6ZNM6; 7.
DR STRING; 9606.ENSP00000349669; -.
DR BioMuta; TEX43; -.
DR MassIVE; Q6ZNM6; -.
DR PaxDb; Q6ZNM6; -.
DR PeptideAtlas; Q6ZNM6; -.
DR PRIDE; Q6ZNM6; -.
DR Antibodypedia; 51544; 71 antibodies from 10 providers.
DR DNASU; 389320; -.
DR Ensembl; ENST00000357147.4; ENSP00000349669.3; ENSG00000196900.5.
DR GeneID; 389320; -.
DR KEGG; hsa:389320; -.
DR MANE-Select; ENST00000357147.4; ENSP00000349669.3; NM_207408.3; NP_997291.1.
DR UCSC; uc003kub.2; human.
DR CTD; 389320; -.
DR GeneCards; TEX43; -.
DR HGNC; HGNC:33767; TEX43.
DR HPA; ENSG00000196900; Tissue enriched (testis).
DR neXtProt; NX_Q6ZNM6; -.
DR OpenTargets; ENSG00000196900; -.
DR PharmGKB; PA162380336; -.
DR VEuPathDB; HostDB:ENSG00000196900; -.
DR eggNOG; ENOG502S426; Eukaryota.
DR GeneTree; ENSGT00390000006935; -.
DR HOGENOM; CLU_131594_1_0_1; -.
DR InParanoid; Q6ZNM6; -.
DR OMA; PKLANNC; -.
DR OrthoDB; 1515620at2759; -.
DR PhylomeDB; Q6ZNM6; -.
DR TreeFam; TF339864; -.
DR PathwayCommons; Q6ZNM6; -.
DR SignaLink; Q6ZNM6; -.
DR BioGRID-ORCS; 389320; 41 hits in 1043 CRISPR screens.
DR GenomeRNAi; 389320; -.
DR Pharos; Q6ZNM6; Tdark.
DR PRO; PR:Q6ZNM6; -.
DR Proteomes; UP000005640; Chromosome 5.
DR RNAct; Q6ZNM6; protein.
DR Bgee; ENSG00000196900; Expressed in sperm and 107 other tissues.
DR Genevisible; Q6ZNM6; HS.
DR GO; GO:0030317; P:flagellated sperm motility; IBA:GO_Central.
DR InterPro; IPR027965; DUF4513.
DR PANTHER; PTHR35247; PTHR35247; 1.
DR Pfam; PF14983; DUF4513; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..134
FT /note="Testis-expressed protein 43"
FT /id="PRO_0000321824"
SQ SEQUENCE 134 AA; 15452 MW; 46CC7F82C8A01BA1 CRC64;
MASGKDTCPT LPKLTNNCSD ESLYKSANKY EEIHLPRFSL KQGMIPRRYV MPWKENMIFR
NVNLKQAEVC GIHTGPLEDS LFLNHSERLC HGEDRKVVFQ KGPPEIKIAD MPLHSPLSRY
QSTVISHGFR RRLV
