TEX44_MOUSE
ID TEX44_MOUSE Reviewed; 530 AA.
AC Q9DA60; A6H651; Q497K4;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 21-MAR-2012, sequence version 2.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Testis-expressed protein 44;
GN Name=Tex44;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q53QW1}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI00498.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AK006136; BAB24427.1; -; mRNA.
DR EMBL; BC100497; AAI00498.1; ALT_INIT; mRNA.
DR EMBL; BC145753; AAI45754.1; -; mRNA.
DR CCDS; CCDS56635.1; -.
DR RefSeq; NP_082242.1; NM_027966.1.
DR AlphaFoldDB; Q9DA60; -.
DR STRING; 10090.ENSMUSP00000136430; -.
DR PhosphoSitePlus; Q9DA60; -.
DR PaxDb; Q9DA60; -.
DR PRIDE; Q9DA60; -.
DR ProteomicsDB; 263288; -.
DR Antibodypedia; 34418; 51 antibodies from 9 providers.
DR Ensembl; ENSMUST00000046004; ENSMUSP00000136430; ENSMUSG00000036574.
DR GeneID; 71863; -.
DR KEGG; mmu:71863; -.
DR UCSC; uc007bvo.2; mouse.
DR CTD; 165100; -.
DR MGI; MGI:1919113; Tex44.
DR VEuPathDB; HostDB:ENSMUSG00000036574; -.
DR eggNOG; ENOG502TDPT; Eukaryota.
DR GeneTree; ENSGT00390000009950; -.
DR HOGENOM; CLU_038692_0_0_1; -.
DR InParanoid; Q9DA60; -.
DR OMA; VENDYMR; -.
DR OrthoDB; 1047581at2759; -.
DR PhylomeDB; Q9DA60; -.
DR TreeFam; TF338437; -.
DR BioGRID-ORCS; 71863; 3 hits in 72 CRISPR screens.
DR PRO; PR:Q9DA60; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q9DA60; protein.
DR Bgee; ENSMUSG00000036574; Expressed in seminiferous tubule of testis and 3 other tissues.
DR Genevisible; Q9DA60; MM.
DR GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR InterPro; IPR031460; DUF4678.
DR PANTHER; PTHR37365; PTHR37365; 2.
DR Pfam; PF15727; DUF4678; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Phosphoprotein; Reference proteome.
FT CHAIN 1..530
FT /note="Testis-expressed protein 44"
FT /id="PRO_0000309183"
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 207..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 305..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..85
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..281
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 364..378
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 468
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q5U2Y8"
FT CONFLICT 111..112
FT /note="AY -> VS (in Ref. 2; AAI45754)"
FT /evidence="ECO:0000305"
FT CONFLICT 146
FT /note="V -> T (in Ref. 2; AAI45754)"
FT /evidence="ECO:0000305"
FT CONFLICT 151..180
FT /note="Missing (in Ref. 2; AAI45754)"
FT /evidence="ECO:0000305"
FT CONFLICT 178
FT /note="S -> Y (in Ref. 1; BAB24427)"
FT /evidence="ECO:0000305"
FT CONFLICT 299
FT /note="N -> T (in Ref. 2; AAI45754)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 530 AA; 56574 MW; 220CF4DDD4F87D1A CRC64;
MTAEPLEDPE ASSSSTHDLP EASSDNTADE NSADLPGESE GPDSLPDDVP PGDIDEVLAE
HDVDQTSEAK AITTEQNEEQ DFIRTDTFMR QDEDLLSKQI STITEKNVDQ AYMQINTVFE
QDKDQASIQT ATLMGQDEDQ AFLQIVTSVG QNKDQASIQT ATLMGQDEDQ ASLQIATSVG
QNKDQPSMQM DTSIGQDVEP AISTDTATSA VKDESPDIPH QGQDNPEETT SLLPQDPGIL
QVFVGFQNPV WDRLAENNRT SRSRTVSPSD SQTQEKTLGN PNVPEGQPVL VPNADVLSNL
PEHVQTSVGA ADPPPSDTSG RDPEPTPTTN SAKQEAEGFK ALNPGSKARS PGLTSEDSAA
DSGIPPDPPD PGSPGGSPPH SPDFYQVALG RNLLDPNLYR PDVENDYMRS MTSLLGCGEG
SISSLTDILV WSDTATRMGV AVGILASGCS SPADRLQDEG PRLRTVASLL RSARSAFSSG
VMSGTGSALH SVTHLLESVE RRTMEGIRSA MRYLAHHLTS RWARTGPSGN
