TEX47_HUMAN
ID TEX47_HUMAN Reviewed; 253 AA.
AC Q8TBZ9;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2002, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Testis-expressed protein 47;
GN Name=TEX47 {ECO:0000312|HGNC:HGNC:22402}; Synonyms=C7orf62;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12853948; DOI=10.1038/nature01782;
RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA Wilson R.K.;
RT "The DNA sequence of human chromosome 7.";
RL Nature 424:157-164(2003).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12690205; DOI=10.1126/science.1083423;
RA Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K.,
RA Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R.,
RA Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A.,
RA Kanematsu E., Gentles S., Christopoulos C.C., Choufani S., Kwasnicka D.,
RA Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S.,
RA Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R.,
RA Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N.,
RA Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E.,
RA Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R.,
RA Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T.,
RA Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W.,
RA Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A.,
RA Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X.,
RA Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E.,
RA Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H.,
RA Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J.,
RA Adams M.D., Tsui L.-C.;
RT "Human chromosome 7: DNA sequence and biology.";
RL Science 300:767-772(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q8TBZ9; Q6FHY5: MEOX2; NbExp=3; IntAct=EBI-12261204, EBI-16439278;
CC -!- TISSUE SPECIFICITY: Testis-specific. {ECO:0000305}.
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DR EMBL; AC002127; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH236949; EAL24169.1; -; Genomic_DNA.
DR EMBL; CH471091; EAW76902.1; -; Genomic_DNA.
DR EMBL; BC028365; AAH28365.1; -; mRNA.
DR CCDS; CCDS34678.1; -.
DR RefSeq; NP_689919.1; NM_152706.3.
DR RefSeq; XP_011514206.1; XM_011515904.2.
DR AlphaFoldDB; Q8TBZ9; -.
DR BioGRID; 128554; 1.
DR IntAct; Q8TBZ9; 1.
DR STRING; 9606.ENSP00000297203; -.
DR iPTMnet; Q8TBZ9; -.
DR PhosphoSitePlus; Q8TBZ9; -.
DR BioMuta; TEX47; -.
DR DMDM; 74730535; -.
DR jPOST; Q8TBZ9; -.
DR MassIVE; Q8TBZ9; -.
DR PaxDb; Q8TBZ9; -.
DR PeptideAtlas; Q8TBZ9; -.
DR PRIDE; Q8TBZ9; -.
DR Antibodypedia; 15398; 61 antibodies from 15 providers.
DR DNASU; 219557; -.
DR Ensembl; ENST00000297203.3; ENSP00000297203.2; ENSG00000164645.3.
DR GeneID; 219557; -.
DR KEGG; hsa:219557; -.
DR MANE-Select; ENST00000297203.3; ENSP00000297203.2; NM_152706.4; NP_689919.1.
DR UCSC; uc003ujv.4; human.
DR CTD; 219557; -.
DR GeneCards; TEX47; -.
DR HGNC; HGNC:22402; TEX47.
DR HPA; ENSG00000164645; Tissue enriched (testis).
DR neXtProt; NX_Q8TBZ9; -.
DR OpenTargets; ENSG00000164645; -.
DR PharmGKB; PA162380726; -.
DR VEuPathDB; HostDB:ENSG00000164645; -.
DR eggNOG; ENOG502RYKR; Eukaryota.
DR GeneTree; ENSGT00390000005565; -.
DR HOGENOM; CLU_089495_0_0_1; -.
DR InParanoid; Q8TBZ9; -.
DR OMA; RLFMQWY; -.
DR OrthoDB; 1274273at2759; -.
DR PhylomeDB; Q8TBZ9; -.
DR TreeFam; TF329731; -.
DR PathwayCommons; Q8TBZ9; -.
DR SignaLink; Q8TBZ9; -.
DR BioGRID-ORCS; 219557; 9 hits in 1047 CRISPR screens.
DR GenomeRNAi; 219557; -.
DR Pharos; Q8TBZ9; Tdark.
DR PRO; PR:Q8TBZ9; -.
DR Proteomes; UP000005640; Chromosome 7.
DR RNAct; Q8TBZ9; protein.
DR Bgee; ENSG00000164645; Expressed in sperm and 30 other tissues.
DR Genevisible; Q8TBZ9; HS.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..253
FT /note="Testis-expressed protein 47"
FT /id="PRO_0000321827"
FT VARIANT 48
FT /note="D -> H (in dbSNP:rs2373396)"
FT /id="VAR_039351"
FT VARIANT 126
FT /note="I -> V (in dbSNP:rs2293583)"
FT /id="VAR_039352"
FT VARIANT 186
FT /note="C -> S (in dbSNP:rs34276371)"
FT /id="VAR_039353"
FT VARIANT 221
FT /note="E -> A (in dbSNP:rs2373398)"
FT /id="VAR_039355"
FT VARIANT 221
FT /note="E -> K (in dbSNP:rs2373397)"
FT /id="VAR_039354"
SQ SEQUENCE 253 AA; 29483 MW; 6D92F6C65D6F7DD5 CRC64;
MSFSVHNQKG SKRPLPLEPL LFLQVPRSNY LHFQEEKQRL HLKKFLLDRM FLVAKIQANV
ERKDVADYYE QMFQSVLKHH LGEAVTGLLL IYPTSILHIL ESSSDTLYKV LLDYIGHVKD
ETVFFIQQMK IIVISHNIPM RLFMQWHVSV IKVPVMYLDD VTQSQSLKEV ITDFLTQTHK
LSLYLCQTMK VGTKGPGDNL HQVAPDLLLP EQIIKYLCKS EEFMDPATFI NMYNRPIHIT
LDSEVVWPAP SRF
