TEX51_HUMAN
ID TEX51_HUMAN Reviewed; 166 AA.
AC A0A1B0GUA7;
DT 30-AUG-2017, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2016, sequence version 1.
DT 03-AUG-2022, entry version 28.
DE RecName: Full=Testis-expressed protein 51 {ECO:0000305};
DE Flags: Precursor;
GN Name=TEX51 {ECO:0000312|HGNC:HGNC:52387};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type I
CC membrane protein {ECO:0000255}.
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DR EMBL; AC114783; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471103; EAW95277.1; -; Genomic_DNA.
DR CCDS; CCDS82507.1; -.
DR RefSeq; NP_001309173.1; NM_001322244.1.
DR RefSeq; XP_016858639.1; XM_017003150.1.
DR AlphaFoldDB; A0A1B0GUA7; -.
DR SMR; A0A1B0GUA7; -.
DR BioMuta; TEX51; -.
DR PeptideAtlas; A0A1B0GUA7; -.
DR DNASU; 101929926; -.
DR Ensembl; ENST00000450035.5; ENSP00000490030.1; ENSG00000237524.10.
DR Ensembl; ENST00000568484.6; ENSP00000489776.1; ENSG00000237524.10.
DR GeneID; 101929926; -.
DR KEGG; hsa:101929926; -.
DR MANE-Select; ENST00000568484.6; ENSP00000489776.1; NM_001322244.2; NP_001309173.1.
DR CTD; 101929926; -.
DR GeneCards; TEX51; -.
DR HGNC; HGNC:52387; TEX51.
DR HPA; ENSG00000237524; Tissue enriched (testis).
DR neXtProt; NX_A0A1B0GUA7; -.
DR OpenTargets; ENSG00000237524; -.
DR VEuPathDB; HostDB:ENSG00000237524; -.
DR GeneTree; ENSGT01040000240573; -.
DR OMA; WIDYDLQ; -.
DR OrthoDB; 1368610at2759; -.
DR BioGRID-ORCS; 101929926; 0 hits in 11 CRISPR screens.
DR GenomeRNAi; 101929926; -.
DR Pharos; A0A1B0GUA7; Tdark.
DR PRO; PR:A0A1B0GUA7; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; A0A1B0GUA7; protein.
DR Bgee; ENSG00000237524; Expressed in right testis and 67 other tissues.
DR ExpressionAtlas; A0A1B0GUA7; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..15
FT /evidence="ECO:0000255"
FT CHAIN 16..166
FT /note="Testis-expressed protein 51"
FT /evidence="ECO:0000255"
FT /id="PRO_0000441046"
FT TRANSMEM 138..154
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 166 AA; 18842 MW; E3F18828247D4FB2 CRC64;
MLPLLIICLL PAIEGKNCLR CWPELSALID YDLQILWVTP GPPTELSQNR DHLEEETAKF
FTQVHQAIKT LRDDKTVLLE EIYTHKNLFT ERLNKISDGL KEKDIQSTLK VTSCADCRTH
FLSCNDPTFC PARNRRTSLW AVSLSSALLL AIAGDVSFTG KGRRRQ
