TEX52_MOUSE
ID TEX52_MOUSE Reviewed; 308 AA.
AC Q3TTI8; Q9D448;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Testis-expressed protein 52 {ECO:0000305};
GN Name=Tex52 {ECO:0000312|MGI:MGI:1918399};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q3TTI8-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q3TTI8-2; Sequence=VSP_034982, VSP_034983;
CC -!- TISSUE SPECIFICITY: Expressed in Testis. {ECO:0000305}.
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DR EMBL; AK016804; BAB30439.1; -; mRNA.
DR EMBL; AK161342; BAE36337.1; -; mRNA.
DR CCDS; CCDS51916.1; -. [Q3TTI8-1]
DR RefSeq; NP_081973.1; NM_027697.1. [Q3TTI8-1]
DR AlphaFoldDB; Q3TTI8; -.
DR SMR; Q3TTI8; -.
DR IntAct; Q3TTI8; 1.
DR STRING; 10090.ENSMUSP00000098486; -.
DR iPTMnet; Q3TTI8; -.
DR PhosphoSitePlus; Q3TTI8; -.
DR PaxDb; Q3TTI8; -.
DR PRIDE; Q3TTI8; -.
DR ProteomicsDB; 262976; -. [Q3TTI8-1]
DR ProteomicsDB; 262977; -. [Q3TTI8-2]
DR Ensembl; ENSMUST00000100926; ENSMUSP00000098486; ENSMUSG00000079304. [Q3TTI8-1]
DR Ensembl; ENSMUST00000130785; ENSMUSP00000145112; ENSMUSG00000079304. [Q3TTI8-2]
DR GeneID; 71149; -.
DR KEGG; mmu:71149; -.
DR UCSC; uc009edm.2; mouse. [Q3TTI8-1]
DR CTD; 101929469; -.
DR MGI; MGI:1918399; Tex52.
DR VEuPathDB; HostDB:ENSMUSG00000079304; -.
DR eggNOG; ENOG502S25Y; Eukaryota.
DR GeneTree; ENSGT00390000006066; -.
DR HOGENOM; CLU_087011_0_0_1; -.
DR InParanoid; Q3TTI8; -.
DR OMA; QHTWGFH; -.
DR OrthoDB; 1543673at2759; -.
DR TreeFam; TF329678; -.
DR BioGRID-ORCS; 71149; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Tex52; mouse.
DR PRO; PR:Q3TTI8; -.
DR Proteomes; UP000000589; Chromosome 6.
DR RNAct; Q3TTI8; protein.
DR Bgee; ENSMUSG00000079304; Expressed in seminiferous tubule of testis and 31 other tissues.
DR Genevisible; Q3TTI8; MM.
DR InterPro; IPR029206; DUF4532.
DR PANTHER; PTHR35156; PTHR35156; 1.
DR Pfam; PF15046; DUF4532; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..308
FT /note="Testis-expressed protein 52"
FT /id="PRO_0000346160"
FT VAR_SEQ 212..230
FT /note="YQYISTGGRLVPWGLQFLP -> HTVSCLPCKRLEAATRVIC (in
FT isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034982"
FT VAR_SEQ 231..308
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_034983"
FT CONFLICT 109
FT /note="A -> T (in Ref. 1; BAB30439)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 308 AA; 35370 MW; 016D1D456792825C CRC64;
MANIPKKTSL QKSSLSQVSR TREPFLKMIH AKESSPIYQT WTQREFLLPK ETKEFPGFTL
QDYHKLALKQ PPCTELKSKV RHQVLYPSKD AAEHTWGFHT WLDVGRLPAT FPTRPDVPYD
SNVWRHLTHA NAHRLPAAQP GIPPPSWMGP HSFLSFISAS PIVVDLKRRK QIIVRTVKEL
KEVEKLKLRS ELRAPPLDAN GNILPPPNFK KYQYISTGGR LVPWGLQFLP NPIPNNICKS
WPCPNHQPHY QEKVLKLARL PTVPLSKDLV KDYQALIKDR LALPVHYLSK ARPAKTPEGK
RKRRPGYV
