TEX55_MOUSE
ID TEX55_MOUSE Reviewed; 381 AA.
AC A6X8Z9; A4QMY3; Q8C5T0;
DT 10-APR-2019, integrated into UniProtKB/Swiss-Prot.
DT 21-AUG-2007, sequence version 1.
DT 03-AUG-2022, entry version 93.
DE RecName: Full=Testis-specific expressed protein 55 {ECO:0000250|UniProtKB:Q96M34};
DE AltName: Full=Testis-specific conserved, cAMP-dependent type II PK-anchoring protein {ECO:0000303|PubMed:19821082};
GN Name=Tex55 {ECO:0000250|UniProtKB:Q96M34};
GN Synonyms=Tscpa {ECO:0000303|PubMed:19821082};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [5]
RP SUBCELLULAR LOCATION, AND TISSUE SPECIFICITY.
RX PubMed=19821082; DOI=10.1007/s11596-009-0502-9;
RA Yu Z., Wu B., Tang A., Chen J., Guo X., Qin J., Gui Y., Cai Z.;
RT "Expression profile of a novel germ cell-specific gene, TSCPA, in mice and
RT human.";
RL J. Huazhong Univ. Sci. Technol. Med. Sci. 29:535-539(2009).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:19821082}.
CC -!- TISSUE SPECIFICITY: Testis-specific. {ECO:0000269|PubMed:19821082}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AK077164; BAC36654.1; -; mRNA.
DR EMBL; CT009576; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH466521; EDK97996.1; -; Genomic_DNA.
DR EMBL; BC115688; AAI15689.1; -; mRNA.
DR CCDS; CCDS49850.1; -.
DR RefSeq; NP_083318.1; NM_029042.1.
DR AlphaFoldDB; A6X8Z9; -.
DR SMR; A6X8Z9; -.
DR iPTMnet; A6X8Z9; -.
DR PhosphoSitePlus; A6X8Z9; -.
DR PaxDb; A6X8Z9; -.
DR PRIDE; A6X8Z9; -.
DR ProteomicsDB; 346922; -.
DR Ensembl; ENSMUST00000122078; ENSMUSP00000113120; ENSMUSG00000022798.
DR GeneID; 74663; -.
DR KEGG; mmu:74663; -.
DR UCSC; uc007zfn.1; mouse.
DR CTD; 152405; -.
DR MGI; MGI:1921913; Tex55.
DR VEuPathDB; HostDB:ENSMUSG00000022798; -.
DR eggNOG; ENOG502SEVH; Eukaryota.
DR GeneTree; ENSGT00940000154487; -.
DR HOGENOM; CLU_034619_0_0_1; -.
DR InParanoid; A6X8Z9; -.
DR OMA; QTDHRLS; -.
DR OrthoDB; 979944at2759; -.
DR TreeFam; TF328421; -.
DR BioGRID-ORCS; 74663; 0 hits in 72 CRISPR screens.
DR ChiTaRS; Tex55; mouse.
DR PRO; PR:A6X8Z9; -.
DR Proteomes; UP000000589; Chromosome 16.
DR RNAct; A6X8Z9; protein.
DR Bgee; ENSMUSG00000022798; Expressed in seminiferous tubule of testis and 4 other tissues.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR InterPro; IPR040760; DUF5582.
DR PANTHER; PTHR47110; PTHR47110; 2.
DR Pfam; PF17819; DUF5582; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..381
FT /note="Testis-specific expressed protein 55"
FT /id="PRO_0000446513"
FT REGION 1..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 47..63
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 64..102
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 124..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 134
FT /note="T -> S (in Ref. 3; EDK97996 and 4; AAI15689)"
FT /evidence="ECO:0000305"
FT CONFLICT 187
FT /note="T -> S (in Ref. 3; EDK97996 and 4; AAI15689)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 381 AA; 43579 MW; 415E4D7FD8FD2FA4 CRC64;
MDEPPDESLN HENTTRAPDN EKNNIEGAGQ ALHRGSEHAG VGSSEPTGDK VSGQANAGSR
QTGRRTSEEA EQRSSQPTEH RLPGHAERRA SQQAERRLSE RRTSQPPNQQ LPSHSERKTS
GKIDGQESLL SEQTDQETSE FDDLIPSAST DYLSARSQQQ EYNQHGYWTE DSSDPHRLSE
DLEKDYTRVK HITEKQAGYR SYYKTLAHIE SRTLTDTNDY RETGQRLQPC TFEDSEAELP
SKVSTTEETE SATTIQAYNT QDTELTTSTS HEKLPSITTK VYYSSSPEKI QTTEYTSDTT
PVFDQGRSSQ RSSQSSRWRF PPIVFEDPYH VALRYVEKHN ILHIFQQITE NLVYERPDDP
LYFMLDQVQN MIKHRDERQS D
