TEX9_MOUSE
ID TEX9_MOUSE Reviewed; 387 AA.
AC Q9D845; B2RUA2; O54764;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Testis-expressed protein 9;
DE AltName: Full=Testis-specifically expressed protein 1;
DE Short=Tsec-1;
GN Name=Tex9;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), AND TISSUE SPECIFICITY.
RC STRAIN=CD-1; TISSUE=Testis;
RX PubMed=9388464; DOI=10.1006/bbrc.1997.7647;
RA Chen L., Sato M., Inoko H., Kimura M.;
RT "Molecular cloning and analysis of novel cDNAs specifically expressed in
RT adult mouse testes.";
RL Biochem. Biophys. Res. Commun. 240:261-268(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=C57BL/6J; TISSUE=Small intestine;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q9D845-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q9D845-2; Sequence=VSP_019570, VSP_019571, VSP_019572;
CC -!- TISSUE SPECIFICITY: Testis-specific. {ECO:0000269|PubMed:9388464}.
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DR EMBL; AB000619; BAA24108.1; -; mRNA.
DR EMBL; AK008505; BAB25705.1; -; mRNA.
DR EMBL; BC141033; AAI41034.1; -; mRNA.
DR CCDS; CCDS40685.1; -. [Q9D845-1]
DR PIR; JC5788; JC5788.
DR RefSeq; NP_033385.2; NM_009359.4. [Q9D845-1]
DR RefSeq; XP_006511083.1; XM_006511020.3.
DR AlphaFoldDB; Q9D845; -.
DR SMR; Q9D845; -.
DR STRING; 10090.ENSMUSP00000139026; -.
DR PhosphoSitePlus; Q9D845; -.
DR MaxQB; Q9D845; -.
DR PaxDb; Q9D845; -.
DR PRIDE; Q9D845; -.
DR ProteomicsDB; 259008; -. [Q9D845-1]
DR ProteomicsDB; 259009; -. [Q9D845-2]
DR Antibodypedia; 42704; 89 antibodies from 19 providers.
DR Ensembl; ENSMUST00000184125; ENSMUSP00000139026; ENSMUSG00000090626. [Q9D845-1]
DR GeneID; 21778; -.
DR KEGG; mmu:21778; -.
DR UCSC; uc009qqa.2; mouse. [Q9D845-1]
DR CTD; 374618; -.
DR MGI; MGI:1201610; Tex9.
DR VEuPathDB; HostDB:ENSMUSG00000090626; -.
DR eggNOG; ENOG502QPKV; Eukaryota.
DR GeneTree; ENSGT00390000018333; -.
DR HOGENOM; CLU_059201_0_0_1; -.
DR InParanoid; Q9D845; -.
DR OMA; SKQMKSC; -.
DR OrthoDB; 1329202at2759; -.
DR PhylomeDB; Q9D845; -.
DR TreeFam; TF327209; -.
DR BioGRID-ORCS; 21778; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Tex9; mouse.
DR PRO; PR:Q9D845; -.
DR Proteomes; UP000000589; Chromosome 9.
DR RNAct; Q9D845; protein.
DR Bgee; ENSMUSG00000090626; Expressed in undifferentiated genital tubercle and 212 other tissues.
DR ExpressionAtlas; Q9D845; baseline and differential.
DR Genevisible; Q9D845; MM.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; Reference proteome.
FT CHAIN 1..387
FT /note="Testis-expressed protein 9"
FT /id="PRO_0000244482"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 58..133
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 184..347
FT /evidence="ECO:0000255"
FT COMPBIAS 74..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 114..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1
FT /note="M -> MYGHHGNRIAPGLVKM (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:9388464"
FT /id="VSP_019570"
FT VAR_SEQ 319..333
FT /note="ITNEDHQKIEVLKSE -> NQYLNNDLERRASN (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:9388464"
FT /id="VSP_019571"
FT VAR_SEQ 334..387
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:9388464"
FT /id="VSP_019572"
SQ SEQUENCE 387 AA; 44066 MW; 5DB3D9DF5DAD2A10 CRC64;
MAGRSVRVPR RGSAGTQSRG QLAAGRDLLA REQEYKRLNE ELEAKTADLV RQAEEVIREQ
QEVRARPFSA LTTSCKEEGG SSSRDLLSSE GTHPWTETKP KTKNTGPVNK IQNRLHSADK
ERKTNSSAKL KYPDAQTAND VAIPDDFSDF SLAKTISRIE GQLDEDGLPE CAEDDSFCGV
SKDIGTEAQI RFLKAKLHVM QEELDSVVCE CSKKEDKIQD LKSKVKNLEE DCVRQQRTVT
SQQSQIEKYK NLFEEANKKC DELQQQLSSV ERELESKRRL QKQAASSQSA TEVRLNRALE
EAEKYKVELS KLRQTNKDIT NEDHQKIEVL KSENKKLERQ KGELMIGFKK QLKLIDILKR
QKMHIEAAKM LSFSEEEFMK ALEWGSS
