TF2B_HALVA
ID TF2B_HALVA Reviewed; 114 AA.
AC P42198;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Transcription initiation factor IIB;
DE Short=TFIIB;
DE Flags: Fragment;
GN Name=tfb;
OS Haloarcula vallismortis (Halobacterium vallismortis).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC Haloarculaceae; Haloarcula.
OX NCBI_TaxID=28442;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 29715 / DSM 3756 / JCM 8877 / NBRC 14741 / NCIMB 2082;
RX PubMed=7708770; DOI=10.1073/pnas.92.7.3036;
RA Seidel R., Scharf B., Gautel M., Kleine K., Oesterhelt D., Engelhard M.;
RT "The primary structure of sensory rhodopsin II: a member of an additional
RT retinal protein subgroup is coexpressed with its transducer, the
RT halobacterial transducer of rhodopsin II.";
RL Proc. Natl. Acad. Sci. U.S.A. 92:3036-3040(1995).
CC -!- FUNCTION: Stabilizes TBP binding to an archaeal box-A promoter. Also
CC responsible for recruiting RNA polymerase II to the pre-initiation
CC complex (DNA-TBP-TFIIB) (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the TFIIB family. {ECO:0000305}.
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DR EMBL; Z35308; CAA84551.1; -; Genomic_DNA.
DR PIR; S55298; S55298.
DR AlphaFoldDB; P42198; -.
DR SMR; P42198; -.
DR STRING; 28442.SAMN05443574_101540; -.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd00043; CYCLIN; 1.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR023486; TFIIB_CS.
DR InterPro; IPR013150; TFIIB_cyclin.
DR PANTHER; PTHR11618; PTHR11618; 1.
DR Pfam; PF00382; TFIIB; 1.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 1.
DR SUPFAM; SSF47954; SSF47954; 1.
DR PROSITE; PS00782; TFIIB; 1.
PE 3: Inferred from homology;
KW Repeat; Transcription; Transcription regulation.
FT CHAIN <1..114
FT /note="Transcription initiation factor IIB"
FT /id="PRO_0000119318"
FT REPEAT <1..17
FT /note="1"
FT REPEAT 28..109
FT /note="2"
FT NON_TER 1
SQ SEQUENCE 114 AA; 12805 MW; 6494F63C4186BB69 CRC64;
VEQKEIGRTY RYVAQELELK MEPVDPKQYV PRFASELELS EEVQSKANEI IDTTAEQGLL
SGKSPTGYAA AAIYAASLLC NEKKTQREVA DVAQVTEVTI RNRYQEQIEA MGIH