TF2B_ORYSJ
ID TF2B_ORYSJ Reviewed; 312 AA.
AC Q8W0W3; Q69K01;
DT 06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Transcription initiation factor IIB;
DE AltName: Full=General transcription factor TFIIB;
GN Name=TFIIB; OrderedLocusNames=Os09g0534800, LOC_Os09g36440;
GN ORFNames=OJ1112_E07.31, P0569E11.1;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND INTERACTION WITH TBP2.
RX PubMed=11971135; DOI=10.1105/tpc.010364;
RA Zhu Q., Ordiz M.I., Dabi T., Beachy R.N., Lamb C.;
RT "Rice TATA binding protein interacts functionally with transcription factor
RT IIB and the RF2a bZIP transcriptional activator in an enhanced plant in
RT vitro transcription system.";
RL Plant Cell 14:795-803(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
CC -!- FUNCTION: General factor that plays a major role in the activation of
CC eukaryotic genes transcribed by RNA polymerase II.
CC {ECO:0000269|PubMed:11971135}.
CC -!- SUBUNIT: Associates with TFIID-IIA (DA complex) to form TFIID-IIA-IIB
CC (DAB-complex) which is then recognized by polymerase II (By
CC similarity). Interacts with TBP2 (PubMed:11971135).
CC {ECO:0000250|UniProtKB:Q00403, ECO:0000269|PubMed:11971135}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the TFIIB family. {ECO:0000305}.
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DR EMBL; AF464908; AAL73491.1; -; mRNA.
DR EMBL; AP005092; BAD33339.1; -; Genomic_DNA.
DR EMBL; AP006067; BAD34211.1; -; Genomic_DNA.
DR EMBL; AP014965; BAT09136.1; -; Genomic_DNA.
DR RefSeq; XP_015651154.1; XM_015795668.1.
DR AlphaFoldDB; Q8W0W3; -.
DR SMR; Q8W0W3; -.
DR STRING; 4530.OS09T0534800-01; -.
DR PaxDb; Q8W0W3; -.
DR PRIDE; Q8W0W3; -.
DR EnsemblPlants; Os09t0534800-01; Os09t0534800-01; Os09g0534800.
DR GeneID; 4347689; -.
DR Gramene; Os09t0534800-01; Os09t0534800-01; Os09g0534800.
DR KEGG; osa:4347689; -.
DR eggNOG; KOG1597; Eukaryota.
DR HOGENOM; CLU_043736_1_1_1; -.
DR InParanoid; Q8W0W3; -.
DR OMA; DHDQRMK; -.
DR OrthoDB; 729732at2759; -.
DR Proteomes; UP000000763; Chromosome 9.
DR Proteomes; UP000059680; Chromosome 9.
DR ExpressionAtlas; Q8W0W3; baseline and differential.
DR Genevisible; Q8W0W3; OS.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0097550; C:transcription preinitiation complex; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017025; F:TBP-class protein binding; IBA:GO_Central.
DR GO; GO:0006352; P:DNA-templated transcription, initiation; IBA:GO_Central.
DR GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR CDD; cd00043; CYCLIN; 2.
DR InterPro; IPR013763; Cyclin-like.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR000812; TFIIB.
DR InterPro; IPR023486; TFIIB_CS.
DR InterPro; IPR013150; TFIIB_cyclin.
DR InterPro; IPR013137; Znf_TFIIB.
DR PANTHER; PTHR11618; PTHR11618; 1.
DR Pfam; PF08271; TF_Zn_Ribbon; 1.
DR Pfam; PF00382; TFIIB; 2.
DR PRINTS; PR00685; TIFACTORIIB.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; SSF47954; 2.
DR PROSITE; PS00782; TFIIB; 1.
DR PROSITE; PS51134; ZF_TFIIB; 1.
PE 1: Evidence at protein level;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Transcription;
KW Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..312
FT /note="Transcription initiation factor IIB"
FT /id="PRO_0000119303"
FT REPEAT 115..192
FT /note="1"
FT REPEAT 216..290
FT /note="2"
FT ZN_FING 2..34
FT /note="TFIIB-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 6
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 9
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 26
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
FT BINDING 29
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00469"
SQ SEQUENCE 312 AA; 34298 MW; 338435FB048C46AF CRC64;
MSDSFCPDCK KHTEVAFDHS AGDTVCTECG LVLEAHSVDE TSEWRTFANE SSDNDPVRVG
GPTNPLLTDG GLSTVIAKPN GAQGEFLSSS LGRWQNRGSN PDRSLILAFR TIANMADRLG
LVATIKDRAN EIYKKVEDLK SIRGRNQDAI LAACLYIACR QEDRPRTVKE ICSVANGATK
KEIGRAKEFI VKQLEVEMGQ SMEMGTIHAG DFLRRFCSTL GMNNQAVKAA QEAVQRSEEL
DIRRSPISIA AAVIYMITQL SDDKKPLKDI SLATGVAEGT IRNSYKDLYP YASRLIPNTY
AKEEDLKNLC TP
