ID   TF2B_SULTO              Reviewed;         308 AA.
AC   Q975S1;
DT   06-JUN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Transcription initiation factor IIB {ECO:0000255|HAMAP-Rule:MF_00383};
DE            Short=TFIIB {ECO:0000255|HAMAP-Rule:MF_00383};
GN   Name=tfb {ECO:0000255|HAMAP-Rule:MF_00383}; OrderedLocusNames=STK_03490;
OS   Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
OS   (Sulfolobus tokodaii).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Sulfurisphaera.
OX   NCBI_TaxID=273063;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 16993 / JCM 10545 / NBRC 100140 / 7;
RX   PubMed=11572479; DOI=10.1093/dnares/8.4.123;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M.,
RA   Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y.,
RA   Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T.,
RA   Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K.,
RA   Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.;
RT   "Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon,
RT   Sulfolobus tokodaii strain7.";
RL   DNA Res. 8:123-140(2001).
CC   -!- FUNCTION: Stabilizes TBP binding to an archaeal box-A promoter. Also
CC       responsible for recruiting RNA polymerase II to the pre-initiation
CC       complex (DNA-TBP-TFIIB). {ECO:0000255|HAMAP-Rule:MF_00383}.
CC   -!- SIMILARITY: Belongs to the TFIIB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00383}.
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DR   EMBL; BA000023; BAB65329.1; -; Genomic_DNA.
DR   RefSeq; WP_010978312.1; NC_003106.2.
DR   AlphaFoldDB; Q975S1; -.
DR   SMR; Q975S1; -.
DR   STRING; 273063.STK_03490; -.
DR   EnsemblBacteria; BAB65329; BAB65329; STK_03490.
DR   GeneID; 42799874; -.
DR   KEGG; sto:STK_03490; -.
DR   PATRIC; fig|273063.9.peg.408; -.
DR   eggNOG; arCOG01981; Archaea.
DR   OMA; RTQKDFA; -.
DR   OrthoDB; 35979at2157; -.
DR   Proteomes; UP000001015; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR   GO; GO:0070897; P:transcription preinitiation complex assembly; IEA:InterPro.
DR   CDD; cd00043; CYCLIN; 2.
DR   HAMAP; MF_00383; TF2B_arch; 1.
DR   InterPro; IPR013763; Cyclin-like.
DR   InterPro; IPR036915; Cyclin-like_sf.
DR   InterPro; IPR000812; TFIIB.
DR   InterPro; IPR023484; TFIIB_arc.
DR   InterPro; IPR023486; TFIIB_CS.
DR   InterPro; IPR013150; TFIIB_cyclin.
DR   InterPro; IPR013137; Znf_TFIIB.
DR   PANTHER; PTHR11618; PTHR11618; 1.
DR   Pfam; PF08271; TF_Zn_Ribbon; 1.
DR   Pfam; PF00382; TFIIB; 2.
DR   PRINTS; PR00685; TIFACTORIIB.
DR   SMART; SM00385; CYCLIN; 2.
DR   SUPFAM; SSF47954; SSF47954; 2.
DR   PROSITE; PS00782; TFIIB; 2.
PE   3: Inferred from homology;
KW   Reference proteome; Repeat; Transcription; Transcription regulation.
FT   CHAIN           1..308
FT                   /note="Transcription initiation factor IIB"
FT                   /id="PRO_0000119337"
FT   REPEAT          124..207
FT                   /note="1"
FT   REPEAT          218..299
FT                   /note="2"
SQ   SEQUENCE   308 AA;  34665 MW;  A7C1A3CF61F9A008 CRC64;
     MSESNKSQAS ATPCPPDKIV FDEERGEYIC TETGEVIEER AIDQGPEWRA FTPEEKEKRS
     RVGGPLNQTI HDMGISTVID WKDKDAMGRT LDPKRRLEVL RWRKWQIRAR IQSSIDRNLA
     QAMNELERIG NLLNLPKAVK DEAALIYRKA VEKGLVRGRS IESVVAASIY AACRRMKMAR
     TLDEIAQFTK ANRKEVARCY RLILRELDIN VPVSDPKDYV TRIGSLLGLS GSTMKMAIDI
     IEKAKESGLT AGKDPAGLAA AAIYIAALLN DERRTQKEIA QIAGVTEVTV RNRYKELTQE
     LKIQIPNQ