ID   TFDC1_DELAC             Reviewed;          25 AA.
AC   P83115;
DT   29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   15-MAR-2004, sequence version 2.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Chlorocatechol 1,2-dioxygenase 1;
DE            EC=1.13.11.-;
DE   AltName: Full=TfdCI;
DE   Flags: Fragment;
GN   Name=tfdC;
OS   Delftia acidovorans (Pseudomonas acidovorans) (Comamonas acidovorans).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Comamonadaceae; Delftia.
OX   NCBI_TaxID=80866 {ECO:0000305};
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND INDUCTION.
RC   STRAIN=MC1 {ECO:0000269|PubMed:12213933};
RX   PubMed=12213933; DOI=10.1099/00221287-148-9-2883;
RA   Benndorf D., Babel W.;
RT   "Assimilatory detoxification of herbicides by Delftia acidovorans MC1:
RT   induction of two chlorocatechol 1,2-dioxygenases as a response to
RT   chemostress.";
RL   Microbiology 148:2883-2888(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=3,5-dichlorocatechol + O2 = (2E,4E)-2,4-dichloromuconate + 2
CC         H(+); Xref=Rhea:RHEA:48572, ChEBI:CHEBI:11438, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:15379, ChEBI:CHEBI:15788;
CC   -!- COFACTOR:
CC       Name=Fe(3+); Xref=ChEBI:CHEBI:29034; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe(3+) ion per subunit. {ECO:0000250};
CC   -!- PATHWAY: Xenobiotic degradation; 2-(2,4-dichlorophenoxy)propanoate
CC       degradation.
CC   -!- INDUCTION: By chemostress caused by the herbicide 2,4-
CC       dichlorophenoxypropionic acid and its metabolites.
CC       {ECO:0000269|PubMed:12213933}.
CC   -!- SIMILARITY: Belongs to the intradiol ring-cleavage dioxygenase family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P83115; -.
DR   SMR; P83115; -.
DR   UniPathway; UPA00348; -.
DR   GO; GO:0051213; F:dioxygenase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Aromatic hydrocarbons catabolism; Dioxygenase; Direct protein sequencing;
KW   Iron; Metal-binding; Oxidoreductase.
FT   CHAIN           1..>25
FT                   /note="Chlorocatechol 1,2-dioxygenase 1"
FT                   /id="PRO_0000085092"
FT   NON_TER         25
FT                   /evidence="ECO:0000303|PubMed:12213933"
SQ   SEQUENCE   25 AA;  2828 MW;  88595C6062BF9016 CRC64;
     MNERVKQVAS ALVDAIQKTL TEQRV