ID   TFIP8_XENLA             Reviewed;         189 AA.
AC   Q6GQ44;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Tumor necrosis factor alpha-induced protein 8;
DE            Short=TNF alpha-induced protein 8;
GN   Name=tnfaip8;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as a negative mediator of apoptosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the TNFAIP8 family. {ECO:0000305}.
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DR   EMBL; BC072904; AAH72904.1; -; mRNA.
DR   RefSeq; NP_001085537.1; NM_001092068.1.
DR   AlphaFoldDB; Q6GQ44; -.
DR   SMR; Q6GQ44; -.
DR   DNASU; 443963; -.
DR   GeneID; 443963; -.
DR   KEGG; xla:443963; -.
DR   CTD; 443963; -.
DR   Xenbase; XB-GENE-941179; tnfaip8.S.
DR   OMA; TEKSHAR; -.
DR   OrthoDB; 1284744at2759; -.
DR   Proteomes; UP000186698; Chromosome 1S.
DR   Bgee; 443963; Expressed in spleen and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; ISS:UniProtKB.
DR   GO; GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; ISS:UniProtKB.
DR   GO; GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
DR   Gene3D; 1.20.1440.160; -; 1.
DR   InterPro; IPR008477; TNFAIP8-like.
DR   InterPro; IPR038355; TNFAIP8_sf.
DR   PANTHER; PTHR12757; PTHR12757; 1.
DR   Pfam; PF05527; DUF758; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Cytoplasm; Reference proteome.
FT   CHAIN           1..189
FT                   /note="Tumor necrosis factor alpha-induced protein 8"
FT                   /id="PRO_0000285722"
SQ   SEQUENCE   189 AA;  21951 MW;  D04BA2B3A37302B1 CRC64;
     MATDIFNSKN LAVQAQKKIL GKMASSKYIA TSLIDDTSGE VLDELYQVTR EYTQNKKDAE
     KITKNLIKTV IKLAVLYRNN QFNEEEIGLM EKFKRKVHQL AMTVVSFYQV EYTFDRNVLS
     KLLNECRELL HQVIQRHLTA KSHGRVNNVF DHFSNCEFLA ALYNPFGPYK KHLQRLCNGV
     NKMLDEDNI