ID   TFKL2_HUMAN             Reviewed;         198 AA.
AC   A6NLC8;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 2.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=TATA-box binding protein associated factor 11 like protein 2 {ECO:0000305};
GN   Name=TAF11L2 {ECO:0000312|HGNC:HGNC:53845};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA   Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA   Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA   Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA   Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA   Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA   Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   TISSUE SPECIFICITY.
RX   PubMed=21078170; DOI=10.1186/1471-2164-11-632;
RA   Tremblay D.C., Alexander G. Jr., Moseley S., Chadwick B.P.;
RT   "Expression, tandem repeat copy number variation and stability of four
RT   macrosatellite arrays in the human genome.";
RL   BMC Genomics 11:632-632(2010).
CC   -!- TISSUE SPECIFICITY: Expressed in fetal brain and testis.
CC       {ECO:0000269|PubMed:21078170}.
CC   -!- SIMILARITY: Belongs to the TAF11 family. {ECO:0000305}.
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DR   EMBL; AC106774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471102; EAX08007.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6NLC8; -.
DR   SMR; A6NLC8; -.
DR   BioMuta; -; -.
DR   EPD; A6NLC8; -.
DR   MassIVE; A6NLC8; -.
DR   PeptideAtlas; A6NLC8; -.
DR   PRIDE; A6NLC8; -.
DR   HGNC; HGNC:53845; TAF11L2.
DR   HPA; ENSG00000284373; Not detected.
DR   neXtProt; NX_A6NLC8; -.
DR   VEuPathDB; HostDB:ENSG00000284373; -.
DR   GeneTree; ENSGT00390000013228; -.
DR   OMA; CIAGLMR; -.
DR   PhylomeDB; A6NLC8; -.
DR   Pharos; A6NLC8; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; A6NLC8; protein.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR   GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR   CDD; cd08048; TAF11; 1.
DR   Gene3D; 1.10.20.10; -; 1.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR045127; TAF11-like.
DR   InterPro; IPR006809; TAFII28_dom.
DR   PANTHER; PTHR13218; PTHR13218; 1.
DR   Pfam; PF04719; TAFII28; 1.
DR   SUPFAM; SSF47113; SSF47113; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..198
FT                   /note="TATA-box binding protein associated factor 11 like
FT                   protein 2"
FT                   /id="PRO_0000332742"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        18..54
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        70..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   198 AA;  21962 MW;  5C6710A2B7C35D29 CRC64;
     METGRQTGVS AEMFAMPRDL KGSKKDGIPE DLDGNLEEPR DQEGELRSED VMDLTEGDNE
     ASASAPPAAK RRKTDTKGKK ERKPTVDAEE AQRMTTLLSA MSEEQLSRYE VCRRSAFPKA
     CIAGLMRSIT GRSVSENVAI AMAGIAKVFV GEVVEEALDV CEMWGEMPPL QPKHLREAVR
     RLKPKGLFPN SNYKKIMF