TFKL4_HUMAN
ID TFKL4_HUMAN Reviewed; 198 AA.
AC A0A1W2PPE2;
DT 03-AUG-2022, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2017, sequence version 1.
DT 03-AUG-2022, entry version 21.
DE RecName: Full=TATA-box-binding protein-associated factor 11-like protein 4 {ECO:0000305};
GN Name=TAF11L4 {ECO:0000312|HGNC:HGNC:53847};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15372022; DOI=10.1038/nature02919;
RA Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T.,
RA Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A.,
RA Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R.,
RA Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L.,
RA Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N.,
RA Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J.,
RA Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A.,
RA Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT "The DNA sequence and comparative analysis of human chromosome 5.";
RL Nature 431:268-274(2004).
RN [2]
RP TISSUE SPECIFICITY.
RX PubMed=21078170; DOI=10.1186/1471-2164-11-632;
RA Tremblay D.C., Alexander G. Jr., Moseley S., Chadwick B.P.;
RT "Expression, tandem repeat copy number variation and stability of four
RT macrosatellite arrays in the human genome.";
RL BMC Genomics 11:632-632(2010).
CC -!- TISSUE SPECIFICITY: Expressed in fetal brain and testis.
CC {ECO:0000269|PubMed:21078170}.
CC -!- SIMILARITY: Belongs to the TAF11 family. {ECO:0000305}.
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DR EMBL; AC106774; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR SMR; A0A1W2PPE2; -.
DR BioMuta; ENSG00000284283; -.
DR PeptideAtlas; A0A1W2PPE2; -.
DR Ensembl; ENST00000638408; ENSP00000491494; ENSG00000284283.
DR GeneCards; TAF11L4; -.
DR HGNC; HGNC:53847; TAF11L4.
DR VEuPathDB; HostDB:ENSG00000284283; -.
DR GeneTree; ENSGT00390000013228; -.
DR OMA; THRIPGH; -.
DR Proteomes; UP000005640; Chromosome 5.
DR RNAct; A0A1W2PPE2; protein.
DR Bgee; ENSG00000284283; Expressed in hindlimb stylopod muscle and 6 other tissues.
DR GO; GO:0005669; C:transcription factor TFIID complex; IBA:GO_Central.
DR GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR GO; GO:0003713; F:transcription coactivator activity; IBA:GO_Central.
DR GO; GO:0051123; P:RNA polymerase II preinitiation complex assembly; IBA:GO_Central.
DR CDD; cd08048; TAF11; 1.
DR Gene3D; 1.10.20.10; -; 1.
DR InterPro; IPR009072; Histone-fold.
DR InterPro; IPR045127; TAF11-like.
DR InterPro; IPR006809; TAFII28_dom.
DR PANTHER; PTHR13218; PTHR13218; 1.
DR Pfam; PF04719; TAFII28; 1.
DR SUPFAM; SSF47113; SSF47113; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..198
FT /note="TATA-box-binding protein-associated factor 11-like
FT protein 4"
FT /id="PRO_0000456144"
SQ SEQUENCE 198 AA; 21660 MW; 99BD2FCCABA2876B CRC64;
METGRQTGVS AEMLAMPRGL KGSKKDGIPE DLDGNLEAPR DQEGELRSED VMDLTEGDSE
ASASAPPAAK RRKTHTKGKK ESKPTVDAEE AQRMTTLLSS MSEEQLSRYE VCRRSAFPRA
RVAGLMRAIT GSSVSENAAI AMAGIAKLFV GEVVEEALDV CEMWGETPPL QPKHLREAVR
RLKPKGLFPN SNCKRIMF